Advances in Heterocyclic Chemistry (eBook)

Cover 1
Advances in Heterocyclic Chemistry, Volume 24 4
Copyright Page 5
Contents 6
Contributors 10
Preface 12
Chapter 1. Quinazolines 14
I. Introduction 14
II. Physical Properties of Quinazolines 15
III. Synthesis of Quinazolines and Quinazolinones 26
IV. Reactions of Quinazolines and Quinazolinones 33
V. Quinazoline N-Oxides 43
VI. Reduced Quinazolines 47
VII. Molecular Rearrangements and Ring Transformations Involving Quinazolines 59
VIII. Naturally Occurring Quinazolines 67
IX. Biologically Active Quinazolines 69
X. Industrial Uses 73
Note Added in Proof 74
Chapter 2. Three-Membered Rings with Two Heteroatoms 76
I. Introduction 76
II. Oxaziridines 77
III. Diaziridines 96
IV. Diazirines 108
Chapter 3. Selenium–Nitrogen Heterocycles 122
I. Introduction 122
II. Five-Membered Selenium–Nitrogen Heterocycles 123
III. Six-Membered Selenium–Nitrogen Heterocycles 157
IV. Miscellaneous Selenium–Nitrogen Heterocycles 161
Chapter 4. Benzo[c]cinnolines 164
I. Introduction: Scope of the Review 165
II. Reactions Leading to the Benzo[c]cinnoline Ring System 165
III. Physical Properties of Benzo[c]cinnolines. Spectra 181
IV. Chemistry of Benzo[c]cinnoline 183
V. Physical and Chemical Properties of Substituted Benzo[c]cinnolines 195
Chapter 5. Developments in the Chemistry of Reissert Compounds (1968–1978) 200
I. Introduction 200
II. Preparation 201
III. Chemical Properties and Reactions 204
IV. Spectral Properties 219
V. Related Compounds and Reactions 219
Note Added in Proof 227
Chapter 6. Current Views on Some Physicochemical Aspects of Purines 228
I. Introduction 228
II. The Ring System 229
III. The Nucleophilic Nature of the 8-Position 235
IV. Group Migration 255
Chapter 7. Advances in Pyrrolizidine Chemistry 260
I. Introduction 261
II. The Synthesis of Pyrrolizidine Derivatives 262
III. Stereochemistry of Pyrrolizidine Bases 287
IV. Spectroscopic Studies 292
V. Reactions of Pyrrolizidine and Its Derivatives 298
VI. Biogenesis of Naturally Occurring Pyrrolizidines 303
Chapter 8. 1,4-Thiazines and Their Dihydro Derivatives 306
I. Introduction 307
II. 1,4-Thiazines 309
III. 1,4-Thiazine 1-Oxides 317
IV. 1,4-Thiazine 1,1-Dioxides 319
V. Dihydro-1,4-thiazines 322
VI. Dihydro-1,4-thiazine 1-Oxides 358
VII. Dihydro-1,4-thiazine 1,1-Dioxides 369
VIII. Conclusion 373
Chapter 9. Recent Advances in Pyridazine Chemistry 376
I. Introduction 376
II. Synthetic Methods 377
III. Reactions 408
IV. Theoretical Calculations 453
V. Physical and Spectral Properties 455
VI. Crystal Structures and Molecular Complexes 462
VII. Biological Activity and Other Uses 464
Cumulative Index of Titles 470