Ionic Actions on Vascular Smooth Muscle
Springer Berlin (Verlag)
978-3-540-07836-4 (ISBN)
This book contains the contributions and discussions of the second symposium on vascular smooth muscles held in Ttibingen in February, 1976. It provides an up-to-date review of the role of ions in the trans mission of signals from the perivascular space to the contractile ele ments of the smooth muscle cells. The various aspects are mainly discussed from a functional point of view and only few contributions concern the morphologic variations of cells .during varying ion activity. Special emphasis was placed on the significance of ion variations in the cerebral tissue and their rela tion to metabolic and nervous control of the brain vessels. It could be seen in this symposium that new techniques enabled the in vestigators to make considerable progress in the understanding of the actions and the interactions of ions on the membranes and on the inter nal structures of the smooth muscle cells if one compares the findings with the results of the previous symposium held in Ttibingen in 1972. It became evident that the insight into ionic actions enables the de velopment of powerful tools to be utilized in future therapy of dis turbances of local blood flow regulation. The participants of the symposium render thanks to the Dr. Thiemann GmbH in Ltinen, which supported the symposium and this publication in a generous way. Finally it is a pleasure of the Editor to thank the members of the Physiological Institute of Ttibingen for their encouragement in the ar rangement of the meeting.
Response Characteristics of K+-, Ca++- and Other Liquid Membrane Electrodes.- Serum Ca++-Activity and Complexation.- Summary of the Discussion. G. Siegel (Chairman) H. Apfel.- Calcium Activation of Vascular Contractile Proteins.- Calcium Compartments in Vascular Smooth Muscle: Electron Probe Analysis.- Differentiation of Calcium Activation Systems in Vascular Smooth Muscle.- La+++ and Excitation Contraction Coupling in Vascular Smooth Muscle.- Summary of the Discussion. G. Siegel (Chairman) and H. Apfel.- Calcium and Regulation of Cyclic Nucleotides in Rat Aorta.- Calcium and the Regulation of Adenosine 3?,5?-Monophosphate by Neurotransmitters.- Summary of the Discussion. A. P. Somlyo (Chairman) and C. Infantes.- Reaction of Capillary Flow to Electrical Stimulation of the Capillary Wall and to Application of Different Ions.- Membrane Basis of Vascular Regulation.- Noradrenaline and pH-Effects at the Membrane of Vascular Smooth Muscle.- Vascular Effects of Potassium in Physiologic Concentration Range.- Summary of the Discussion. W. R. Keatinge (Chairman) and U. Schindler.- Calcium in the Vascular Smooth Muscle Cell.- Spontaneous Actions of Small Pial Vessels and the Response to Transmural Electrical Stimulation.- Ionic Interaction in Pial Vascular Smooth Muscles.- Measurements of Pial Perivascular Ion Activities by Means of Ion Sensitive Microelectrodes.- The Effects of Serotonin and Noradrenaline on the Pial Arteries.- Interactions of Norepinephrine with H+ and K+ at Pial Arteries of Cats.- Summary of the Discussion. J. Astrup (Chairman) and G. Karlitzky.- The Action of K+ at the Cerebral Vessels.- K+ Accumulation as a Pathological Stimulus for Dilatation or Contraction of Cerebral Vessels.- H+, CO2, Prostaglandins and Cerebrovascular Smooth Muscle.- Correlation ofChanges in Blood Flow and Acid-Base Changes in the Brain during Induced Epileptic Seizures.- Evidence against H+ and K+ as the Main Factors in the Regulation of Cerebral Blood Flow during Epileptic Discharges, Acute Hypoxemia, Amphetamine Intoxication, and Hypoglycemia. A Microelectrode Study.- Summary of the Discussion. R. M. Berne (Chairman) and D. Heuser.- Interactions of H Ions, Ca-Antagonistic Drugs and Cardiac Glycosides with Excitation-Contraction Coupling of Vascular Smooth Muscle.- Effect of Phosphodiesterase-Inhibition on Smooth Muscle Tone.- The Effect of Bencyclane on the K+- and Ca++- Induced Pial Arterial Constriction.- Effect of Adenosine on Contraction of Vascular Smooth Muscle.- Influence of pH on Adenosine-Induced Dilatations of Pial Arteries.- Effect of Sodium Nitroprusside, Temperature, and Calcium Withdrawal on the Relaxation Speed of Vascular Smooth Muscle.- Summary of the Discussion. C. van Breemen (Chairman) and A. Linke.- Conclusion.
| Erscheint lt. Verlag | 1.8.1976 |
|---|---|
| Zusatzinfo | XVI, 158 p. 5 illus. |
| Verlagsort | Berlin |
| Sprache | englisch |
| Maße | 170 x 244 mm |
| Gewicht | 295 g |
| Themenwelt | Sachbuch/Ratgeber ► Natur / Technik ► Naturführer |
| Medizin / Pharmazie ► Allgemeines / Lexika | |
| Schlagworte | adenosine • brain • Calcium • Cell • Muscle • therapy |
| ISBN-10 | 3-540-07836-3 / 3540078363 |
| ISBN-13 | 978-3-540-07836-4 / 9783540078364 |
| Zustand | Neuware |
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