Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors

An examination of tumours of the nervous system, which focuses on specific molecular-genetic defects in neural tumours and their potential clinical significance. The contributors also provide an update of established and novel treatment regimens for patients with brain tumours.

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Tumours of the nervous system represent a difficult therapeutic challenge. During recent years, substantial progress has been made in characterizing genetic mechanisms involved in the formation of brain tumours. There is a lot of hope that an understanding of the molecular basis of transformation will eventually lead to specific therapeutic approaches. In this volume, leading authorities in both molecular and clinical neuro-oncology summarize recent developments in their respective fields. The first part of the book will focus on specific molecular genetic defects in neural tumours and their potential clinical significance. Part two gives an update on established and novel treatment regimens for patients with brain tumours. Several contributions will demonstrate that molecular and clinical neuro-oncology are already connected. With its unique combination of molecular biological and clinical data, this volume provides basic researchers and clinical neuroscientists with a comprehensive update in both disciplines.