Oxidative Injury in Dermatopathology

This volume aims to serve as an information source for cutaneous biologists, dermatologists and biomedical scientists interested in free radicals and reactive oxygen species and their role in skin pathology.

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This book aims to serve as a source of information for cutaneous biologists, dermatologists and biomedical scientists interested in free radicals and reactive oxygen species and their role in skin pathology. It covers all aspects of oxidative stress, including its importance in basic pathologic processes, as well as in skin diseases, dermatopharmacology and dermatotoxicology. A large data base of references is also provided. In the introduction, the physicochemical properties and production and target sites of reactive oxidants in the skin are discussed. The antioxidant systems of the skin are then described, and the participation of oxidants and antioxidants in basic pathophysiologic events is analyzed. Finally, specific aspects of oxidative injury in selected skin diseases, pharmacology and toxicology are investigated. The book deals in detail with many areas of cutaneous biology and clinical dermatology from the perspective of a 'free radical' scientist and physician, and should serve as a cornerstone in this rapidly changing area of cutaneous biology research.