Biological Response Modifiers - Interferons, Double-Stranded RNA and 2',5'-Oligoadenylates

This volume provides a summary of current knowledge regarding the interferon-based natural antiviral protection system, including 2,5-oligoadenylate and double-stranded RNA. It aims to develop a solid rationale for the use of heterologous immunomodulators in clinical practice.

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Biological response modifiers are increasingly used in viral and cancer therapy. Since alterations of the immune system are the primary symptoms of HIV infection, therapies directed towards the modulation of the immune response have been under intense evaluation. This volume summarizes the current knowledge of the interferon-based natural antiviral protection system, including 2',5'-oligoadenylate and double-stranded RNA. It should help to develop a solid scientific rationale for the practical use of heterologous immunomodulators in the clinics.