Detection of Highly Dangerous Pathogens

Tania Kostic is a researcher in the Department of Bioresources/Microbiology at the Austrian Research Centers at Seibersdorf working on microbial diagnostic microarrays. Patrick Butaye is a veterinary researcher at the Veterinary and Agrochemical Research Center in Brussels with a focus on antimicrobial resistance in bacteria from animal origin. Jacques Schrenzel is a physician and microbiologist, heading the central bacteriological laboratory of the Hôpitaux Universitaires de Genève. He is also a consultant for infectious diseases and is in charge of the genome research laboratory.

Preface (Kostic, Butaye, Schrenzel)
Introduction on Microarray-based Detection Methods (Schrenzel, Kostic, Bodrossy, Francois)
METHODS
Long-oligonucleotide Microarray-based Microbial Detection (Kostic, Bodrossy)
Sequence-specific End-labelling of Oligonucleotides (SSELO) (Kostic, Bodrossy)
Non-cognate Approaches for Pathogen Detection on Microarrays (Schrenzel, Francois, Hernandez, Hibbs, Huyghe, Charbonnier)
Patterning Techniques for Array Platforms (Piskin, Garipcan, Demirel, Caglayan)
Probe Immobilization Techniques in Array Technologies (Piskin, Caglayan, Duman)
IDENTIFICATION
Low-Cost-and-Density (LCD)-Microarrays - a Novel Technique for Identification and Typing of Microorganisms (Frangoulidis, Heiser, Landt, Meyer)
DNA Microarray Technique for Detection and Identification of Viruses Causing Encephalitis and Hemorrhagic Fever (Nordstroem, Falk, Nilsson, Lundkvist)
Microarrays for genomotyping of pathogens (Kieboom, Voskamp, Broekhuijsen)
TYPING
Single Nucleotide Polymorphisms (SNPs) as Targets for DNA-array Based Identification and Typing of BSL3 Bacteria (Wattiau, Vos, Fretin)
Use of a Microchip to Detect Antibiotic Resistance Genes in Bacillus anthracis (Perreten, Frey)
QUALITY CONTROL
Progress Toward Development of Microarrays for Routine Diagnostic Use for Detection of Select High Risk Pathogens (Kempsell, Shah, Sherwin, Vipond, Silman)