Basic and Applied Mutagenesis

I. Introduction.- Welcoming Address.- Inaugural Address.- Toxins in the Human Food System.- II. Risks to Human Health Induced by Pesticides.- General Human Health Risks Associated with the Use of Chemicals.- Water Contamination and Environmental Mutagens.- Problems Associated with the Use of Chemicals by Agricultural Workers.- Mechanism of Contamination from Agricultural Chemicals in Mammals.- Mycotoxins as Carcinogens.- III. Basic Studies Related to Mutagenesis and Carcinogenesis.- Cytotoxicity as a Mechanism of Carcinogenesis.- Mutagenesis-Enhancement by Plasmids in Mutagenesis Tester Strains.- Situation-Dependent Repair of DNA Damage in Yeast.- A Possible Role for Deoxyribonucleotide Pool Imbalances in Carcinogenesis.- Polysubstrate Monooxygenases in Drosophila, Mammals and Man.- IV. Mutagenic, Teratogenic, and Predictive Carcinogenic Studies of Pesticides.- Evaluation of the Genotoxic Potential of Certain Pesticides Used in Pakistan.- Mutagen Testing of Agricultural Chemicals with Yeast.- Plant Genetic Assays and their Use in Studies on Environmental Mutagenesis in Developing Countries.- Aneuploidy Induced by Agricultural Pesticides: Where Do We Stand?.- The Science of Teratology in a Regulatory Setting.- V. Appendix I - Protocols.- Mutagen Testing with Yeast.- Mutagen Testing with Maize.- Mutagen Testing with the Soybean Assay.- The Micronucleus Test on Exfoliated Human Cells.- Mutagenicity Testing with Drosophila melanogaster.- A FORTRAN Program for the Construction of Selby-Olson Tables.- VI. Appendix Psticides Registered in Pakistan.- Agricultural Chemicals Registered for Sale in Pakistan.- Author Index.- Chemical Index.