Nanofluidics

"Joshua B. Edel received his PhD in physical chemistry at Imperial College London in 2004. His thesis focused on the development of single molecule detection within microfluidic systems. He then moved to Cornell University for postdoctoral training in nanobiotechnology. In 2005, Dr Edel was awarded a research fellowship at the Rowland Institute, Harvard University to study the structure and interactions of biomolecules in their native cellular environment. In July 2006, he accepted a joint lectureship at the Institute of Biomedical Engineering and the Department of Chemistry, Imperial College London. His current research focuses on the development of nanofluidic devices to further understand biophysical systems at the single molecule level. He has published 22 research articles, 13 conference proceedings, 1 book chapter and has 5 patents and patent applications to his name. Andrew J. deMello received his PhD in molecular photophysics at Imperial College London in 1995. His post-doctoral studies at the University of California, Berkeley focused on the application of microfluidic systems for DNA analysis and resulted in the first demonstration of PCR amplification, separation and detection of DNA on an integrated microchip. He has been on the faculty of the Chemistry Department at Imperial College since 1997 and now holds the Chair of Chemical Nanosciences. His research centres on miniaturized chemical analysis systems and ultra-high sensitivity detection. More generally, studies focus on performing chemistry and biology in pico- to nanoliter volumes, high-efficiency manipulation of small liquid samples and investigating novel phenomena on the micro- and nanoscale. In 2002, he was awarded the SAC Silver Medal by the Royal Society of Chemistry for his contributions to the Analytical Sciences and in 2004 became a Fellow of the Royal Society of Chemistry."

"Chapter 1: Transport of Ions, DNA Polymers, and Microtubules in the Nanofluidic Regime;

Chapter 2: Biomolecule Separation, Concentration, and Detection using Nanofluidic Channels;

Chapter 3: Particle Transport in Micro and Nanostructured Arrays: Asymmetric Low Reynolds Number Flow;

Chapter 5: Fabrication of Silica Nanofluidic Tubing for Single Molecule Detection;

Chapter 6: Single Molecule Analysis Using Single Nanopores;

Chapter 7: Nanopore-Based Optofluidic Devices for Single Molecule Sensing;

Chapter 8: Ion-Current Rectification in Nanofluidic Devices;

Chapter 9: Nanopillars and Nanoballs for DNA Analysis;"