Pharmaceutical Dosage Forms - Parenteral Medications

Sandeep Nema Ph.D. is Executive Director, Pharmaceutical R&D, BioTherapeutics Pharmaceutical Sciences at Pfizer in St. Louis. Since graduating in 1992 with his doctorate, Dr. Nema has been involved with the development of small molecule and protein drugs via parenteral delivery, first at Mallinckrodt Medical and then at Pfizer (Searle, Pharmacia), and has led the formulation of four launched products. He is active in the American Association of Pharmaceutical Scientists (AAPS) and the Parenteral Drug Association (PDA), where he has chaired several meetings and focus groups. Dr. Nema holds an adjunct faculty appointment at the University of Tennessee. John D. Ludwig Ph.D. is Vice President, Business Strategy, Operations, and Clinical Supply Planning, BioTherapeutics Pharmaceutical Sciences at Pfizer, and Site Director for the company’s St. Louis Laboratories. Dr. Ludwig received a B.S. degree in Pharmacy and Ph.D. degree in Pharmaceutics from the University of Tennessee, Memphis and has held numerous research and development positions at Burroughs Wellcome Co, Searle, Inc., Pharmacia, Inc., and Pfizer. He is active in the American Association of Pharmaceutical Scientists (AAPS) and the Parenteral Drug Association (PDA) Training and Research Institute, where he has contributed to developing professional training courses and has regularly served as an instructor.

Volume I 1 Parenteral Dosage Forms: Introduction and Historical Perspectives 2 Parenteral Drug Administration: Routes of Administration and Devices 3 Biopharmaceutics and Immunogenicity of Biotherapeutics 4 Preformulation Research of Parenteral Medication 5 Formulation Development of Small and Large Volume Injections 6 Solubility and Solubilization 7 Formulation of Depot Delivery Systems 8 Biophysical and Biochemical Characterization of Peptide and Protein Drug Product 9 Formulation of Protein- and Peptide-based Parenteral Products 10 Development of Ophthalmic Formulations 11 Glass containers for Parenteral Products 12 Plastic Packaging for Parenteral Drug Delivery 13 Elastomeric Closures for Parenterals 14 Parenteral Product Container-Closure Integrity Testing