Reproductive Toxicology

Robert W. Kapp, Rochelle W. Tyl

Section I: Normal Reproduction and Development. 1. Biology and Physiology of Fertilization. 2. Normal Development of the Male Reproduction System. 3. Normal Development of the Female Reproduction System. 4. Development of the Mammalian Nervous System. Section II: Regulatory Evaluation of Reproduction. 5. EPA and OECD Perspectives on Reproductive and Developmental Toxicity Testing. 6. FDA and ICH Perspectives on Reproductive and Developmental Toxicity Testing. 7. Reproductive Study Evolution and IND Submissions. Section III: Developmental Toxicity of Systemic Organ Systems. 8. Developmental Immunotoxicity. 9. Developmental Neurotoxicity. 10. Developmental Toxicology of the Respiratory System. 11. Developmental Toxicology of the Renal System. 12. Developmental Toxicology of the Liver. 13. Cardiovascular Development and Malformation. Section IV: Toxicity of the Reproductive Process. 14. Male Reproductive Toxicity. 15. Female Reproductive Toxicity. 16. Toxicity of Pregnant Female Reproductive System. 17. Epigenetic Reproductive Toxicants. 18. Endocrine Disruption Effects on Reproductive Development and Adult Reproduction. 19. Metals and Metal Compounds in Reproductive and Developmental Toxicology. 20. -omics in Reproductive and Developmental Toxicology.