Arthritis Research
Humana Press Inc. (Verlag)
978-1-58829-918-5 (ISBN)
In Volume 1, authors discuss synovial joint morphology, histopathology, and immunohistochemistry, cartilage matrix and bone biology, and cell trafficking, migration and invasion. Volume 2 is broken up into sections that cover immunobiology and T cells, animal models of arthritis, and applications of new technologies, such as Differential Display Reverse Transcription-Polymerase Chain Reaction (DDRT-PCR), to define novel therapeutic targets. Both volumes combine to produce a concise set of protocols condensing decades of experience and expertise.
Arthritis Research: Methods and Protocols will be a valuable tool for basic research investigators, clinician scientists, pathologists, immunologists, and biochemists looking to stay current in their fields.
Immunobiology.- Phenotypic Analysis of B-Cells and Plasma Cells.- Detection of Antigen Specific B-Cells in Tissues.- Single Cell Analysis of Synovial Tissue B-Cells.- Tracking Antigen Specific CD4+ T-Cells With Soluble MHC Molecules.- Analysis of Antigen Reactive T-Cells.- Identification and Manipulation of Antigen Specific T-Cells with Artificial Antigen Presenting Cells.- Analysis of Th1/Th2 T-Cell Subsets.- Analysis of the T-Cell Receptor Repertoire of Synovial T-Cells.- The Assessment of T-Cell Apoptosis in Synovial Fluid.- Assays of T-Cell Contact Dependent Monocyte-Macrophage Functions.- Phenotypic and Functional Analysis of Synovial Natural Killer Cells.- Identification and Isolation of Synovial Dendritic Cells.- Animal Models of Arthritis.- The Use of Animal Models for Rheumatoid Arthritis.- Collagen-Induced Arthritis in Mice.- Collagen-Induced Arthristis in Rats.- Collagen Antibody Induced Arthritis.- Arthritis Induced with Minor Cartilage Proteins.- Murine Antigen-Induced Arthritis.- Pristane-Induced Arthritis in the Rat.- The K/BxN Mouse Model of Inflammatory Arthritis.- Analysis of Arthritic Lesions in the Del1 Mouse.- Application of New Technologies to Define Novel Therapeutic Targets.- Gene Expression Profiling in Rheumatology.- Differential Display Reverse Transcription-Polymerase Chain Reaction to Identify Novel Biomolecules in Arthritis Research.- Two-Dimensional Electrophoresis of Proteins Secreted from Articular Cartilage.- Mapping Lymphocyte Plasma Membrane Proteins.- In Vivo Phage Display Selection in the Human/SCID Mouse Chimera Model for Defining Synovial Specific Determinants.- Adenoviral Targeting of Signal Transduction Pathways in Synovial Cell Cultures.
Erscheint lt. Verlag | 6.7.2007 |
---|---|
Reihe/Serie | Methods in Molecular Medicine ; 136 |
Zusatzinfo | 6 Illustrations, color; 73 Illustrations, black and white; XXII, 432 p. 79 illus., 6 illus. in color. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 152 x 229 mm |
Themenwelt | Medizinische Fachgebiete ► Chirurgie ► Unfallchirurgie / Orthopädie |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Orthopädie | |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Naturwissenschaften ► Biologie ► Zellbiologie | |
ISBN-10 | 1-58829-918-X / 158829918X |
ISBN-13 | 978-1-58829-918-5 / 9781588299185 |
Zustand | Neuware |
Haben Sie eine Frage zum Produkt? |
aus dem Bereich