Vibrio cholerae and Cholera

Molecular to Global Perspectives

I Kaye Wachsmuth, Paul a Blake, Orjan Olsvik (Autoren)

Buch | Hardcover

478 Seiten

1994
American Society for Microbiology (Verlag)
978-1-55581-067-2 (ISBN)

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Addressing the recent arrival of the seventh cholera pandemic in the Western Hemisphere, this book considers its increased importance in Africa and Asia during the past two years. The research also contrasts the pandemic with low-level endemic disease in Australia and the United States.

Presents the latest molecular studies of virulence, colonization, gene regulation, and the O1 antigen. Gives an in-depth and analytical approach to the epidemiology of cholera that includes outbreak investigations, case-control studies, and surveillance functions. Describes the molecular approach to epidemiologic problems and questions. Tracks the global spread of cholera by genetically defining individual strains. Addresses possible intervention and prevention strategies, including the latest vaccines, and their public health relevance.

This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.

Introduction; The bacterium Vibrio cholerae,; Isolation and identification of toxigenic Vibrio cholerae 01 from fecal specimens; Toxigenic Vibrio cholerae in food and water; Detection of cholera toxin genes; Detection of toxins of Vibrio cholerae 01 and non-01; Non-toxigenic Vibrio cholerae 01 infections in the United States; Molecular basis for O-antigen biosynthesis in Vibrio cholerae 01; Ogawa-Inaba switching; Non-O group 1 Vibrio cholerae; Vibrios in the environment; Serologic diagnosis of Vibrio cholerae 01 infection; Virulence factors; Toxins of Vibrio cholerae 01; Regulation of toxin (CT) expressions; The toxin-coregulated pilus: biogenesis and function; Animal models in cholera research; Cholera: the disease; Cholera: pathophysiology; Immunity to Vibrio cholerae infection; Host susceptibility; Epidemiology and surveillance; Cholera before 1970; The African epidemic 1970-92; Endemic cholera in Australia and the United States; The Latin American epidemic; Transmission of cholera; Molecular epidemiology of Vibrio cholerae 01; Cholera surveillance; Vaccines; Polysaccharide-protein conjugate vaccines for prevention of cholera; Molecular recombinant cholera vaccines; Protective oral cholera vaccine based on a combination of cholera toxin B subunit and inactivated Cholera vibrios; Public health consideration for the use of cholera vaccines in cholera control programs; Cholera: the future; Cholera: unanswered questions

Verlagsort	Washington DC
Sprache	englisch
Themenwelt	Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Geowissenschaften ► Geografie / Kartografie
ISBN-10	1-55581-067-5 / 1555810675
ISBN-13	978-1-55581-067-2 / 9781555810672
Zustand	Neuware