Sigma Receptors
Springer-Verlag New York Inc.
978-0-387-36512-1 (ISBN)
Contributing Authors.- Preface.- s Receptors: Historical Perspective and Background.- Medicinal Chemistry: New Chemical Classes and Subtype Selective Ligands.- Irreversible s Compounds.- Pharmacophore Models for s1 Receptor Binding.- Cloning of s1 Receptor and Structural Analysis of its Gene and Promoter Region.- Site-Directed Mutagenesis.- s Receptor Modulation of Ion Channels.- Subcellular Localization and Intracellular Dynamics of s1 Receptors.- Intracellular Signaling and Synaptic Plasticity.- Modulation of Classical Neurotransmitter Systems by s Receptors.- s2 Receptors: Regulation of Cell Growth and Implications for Cancer Diagnosis and Therapeutics.- Cognitive Effects of s Receptor Ligands.- s Receptors and Schizophrenia.- Potential Role of s1 Ligands and Neurosteroids in Major Depression.- s Receptors and Drug Abuse.- s1 Receptors and Modulation of Opiate Analgesics.- s Receptors in the Immune System: Implications for Potential Therapeutic Intervention - an Overview.- s Receptors and Gastrointestinal Function.- Appendix.
Zusatzinfo | 38 Tables, black and white; X, 413 p. |
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Verlagsort | New York, NY |
Sprache | englisch |
Maße | 155 x 235 mm |
Gewicht | 805 g |
Themenwelt | Medizin / Pharmazie ► Studium |
Naturwissenschaften ► Biologie ► Humanbiologie | |
Naturwissenschaften ► Biologie ► Zellbiologie | |
Naturwissenschaften ► Chemie | |
ISBN-10 | 0-387-36512-5 / 0387365125 |
ISBN-13 | 978-0-387-36512-1 / 9780387365121 |
Zustand | Neuware |
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