Thyroid Disease

Part 1 Historical introduction: thyroidology - reflections on 20th century history. Part 2 Basic clinical sciences: surgical anatomy and embryology of the lower neck and superior mediastinum; physiology of thyroid hormone synthesis, secretion and transport; clinical approach to thyroid function testing; parathyroid function and calcium homeostasis; pathology of thyroid disease; fine needle biopsy of the thyroid; uptake tests, thyroid and whole body imaging with isotopes; diagnostic imaging of the thyroid gland. Part 3 Molecuar biology of the thyroid gland: molecular basis of thyroid disease; molecular biology of the TSH receptor; thyroid hormone resistance syndromes; oncogenes and thyroid cancer. Part 4 Hyperthyroidism: hyperthyroidism - systematic effects and differential diagnosis; medical management of hyperthyroidism - theoretical and practical aspects; treatment of hyperthyroidism with 131-I; surgical treatment of hyperthyroidism; thyroid-associated ophthalmology - aetiology and pathogenesis; thyroid associated ophthalmology - treatment. Part 5 Hypothyroidism: clinical manifestations and differential diagnosis of hypothyroidism. Part 6 Thyroiditis - nodular and congenital thyroid disease: thyroiditis; solitary thyroid nodule - concepts in diagnosis and treatment; multinodular goiter; management of substernal thyroid disease; management of thyroid disorders involving the airway; congential thyroid cysts and ectopic thyroid. Part 7 Treatment with thyroid hormone: replacement and suppressive treatment with thyroid hormone. Part 8 Thyroid cancer: thyroid cancer - controversies and aetiopathogenesis; evaluation and surgical treatment of papillary and follicular carcinoma; thyroglobulin in benign and malignant thyroid disease; 131-I and external radiation in the treatment of local metastic thyroid cancer; medullary and thyroid carcinoma and the multiple endocrine neoplasia syndromes; anaplastic carcinoma, lymphona and the unusual malignancies, and chemotherapy for thyroid cancer; management of thyroid carcinoma invading the upper aerodigestive system. Part 9 Surgery of the thyroid gland: general and regional anaesthesia for thyroid surgery; the technique of thyroidectomy by cervical and thoracic approaches; complications of thyroid surgery - an overview; nonmetabolic complications of thyroid surgery; metabolic complications of thyroid surgery; metabolic complications of thyroid surgery - thyrotoxic storm.