Neuro-Nutraceuticals and Drug Discovery and Delivery in Alzheimer’s Disease
Apple Academic Press Inc. (Verlag)
978-1-77491-944-6 (ISBN)
The number of people living with dementia is expected to rise from 55 million in 2019 to 139 million in 2050, according to a report by WHO. Treatments and potential cures for Alzheimer’s have been researched for a long time now. Conventional drugs, while providing symptomatic relief, have often fallen short of halting the relentless progression of this neurodegenerative disorder. This new two-volume set, Neuro-Nutraceuticals and Drug Discovery and Delivery in Alzheimer’s Disease, 2-volume set, represents a collective effort to delve into the potential of nature’s pharmacopeia in our battle against Alzheimer’s disease. The editors posit that essential insights into the intricacies of the disease are the foundation for subsequent discussions on potential therapeutic interventions.
Volume 2: Strategies to Unlock the Brain’s Fortress offers a comprehensive exploration into the cutting-edge strategies for the pursuit of effective Alzheimer’s management. The first section of this volume is dedicated to a holistic exploration of nutraceuticals and their pivotal role in managing Alzheimer’s disease, serving as a guide to the diverse array of neuro-nutraceuticals and providing insights into their mechanisms, efficacy, and potential integration into holistic Alzheimer’s management strategies. The chapter authors look at natural antioxidant therapeutics, natural steroidal phytopharmaceuticals and Terpenes (aromatic compounds found in many plants), anti-apoptotic natural products, polysaccharides, neuro-protective role of vitamin D, non-flavonoidal agents for the effective treatment of Alzheimer’s. Recent developments and advancements in the delivery of nutraceuticals are explored as well, looking at nanotechnology and advanced drug delivery systems for therapeutic interventions in Alzheimer’s disease.
Together, these volumes not only reflect the current state of knowledge but also pave the way for future exploration in the field. Neuro-Nutraceuticals and Drug Discovery and Delivery in Alzheimer’s Disease will enlighten readers, whether seasoned researchers, practitioners, or advanced students, with a wealth of scientific knowledge gained through the cutting-edge research and in-depth exploration of the therapeutic potential of nature’s offerings and shall contribute to the ongoing efforts in managing dementia and cognitive disorders.
Varinder Singh, PhD, is working as Assistant Professor in the Department of Pharmaceutical Sciences and Technology at Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab, India. His research interests primarily lie in the discovery and development of natural products for therapeutic use. He is well-versed in the fields of natural product chemistry (isolation and characterization of bioactive natural compounds), drug discovery, and pharmacology. He has a strong record of publications in high-impact peer-reviewed journals (39 peer-reviewed publications), with many of his papers cited extensively in the field of natural products. He has one patent granted. He has been awarded with numerous travel grants from government and non-government organizations, including the Alzheimer’s Association International, the Indian Department of Science and Technology, Indian Council of Medical Research, and International Brain Research Organization. He earned his PhD (Pharmaceutical Sciences) at Punjabi University, Patiala, Punjab, India. Amit Kumar, PhD, is working as Associate Professor at Chitkara College of Pharmacy, Chitkara University, Punjab, India. He has 12 years of teaching and research experience and has published more than 20 research articles in international journals. He has to date 371 citations and an h-index of 11. He has filed three patents. His area of research includes neuroprotective drug development and elucidating pathological features of diseases. He has received various awards and grants from the International Brain Research Organization, the Indian Department of Science and Technology (DST)-Science and Engineering Research Board, and the Indian Council of Medical Research. He is a certified trainer of Scientific Medical Writing approved from the Life Sciences Sector Skill Development Council and DST (Govt. of India). He received his graduate, postgraduate, and PhD degrees in Pharmaceutical Sciences from Punjabi University Patiala, Punjab, India. Parul Sood, PhD, is working as an Associate Professor at Chitkara School of Pharmacy, Chitkara University, Himachal Pradesh, India. She has more than 14 years of professional experience in teaching and research. Her area of specialization and research is exploring herbal plants for the treatment of various neurological disorders including, Alzheimer’s disease, as well as pharmacognostical and phytochemical evaluation, and standardization of herbal drugs and herbal drug formulation development. She is a gold medalist in MPharm and GATE as well as GPAT qualified. She has a total of 12 publications in reputed journals and has presented a total of 15 oral/poster presentations at national and international conferences and was awarded third position at two national conferences. She completed her PhD at the Department of Pharmaceutical Sciences, Punjabi University Patiala, Punjab, India.
PART I: NUTRACEUTICALS: HOLISTIC APPROACHES TO ALZHEIMER’S MANAGEMENT 1. Emergent Natural Antioxidant Therapeutics to Cope with Oxidative Stress in Alzheimer’s Disease 2. Exploring Beta Secretase Inhibitors as the Evergreen Drug Target for Alzheimer’s Disease: Calling Herbal Therapies to the Rescue 3. Role of Natural Steroidal Phytopharmaceuticals in the Management of Alzheimer’s Disease 4. Potential Role of Terpenes in the Management of Alzheimer’s Disease 5. Anti-Apoptotic Natural Products for the Management of Alzheimer’s Disease 6. Potential Natural Polysaccharides for the Management of Alzheimer’s Disease 7. Neuro-Protective Role of Vitamin D in Alzheimer’s Disease 8. Role of Non-Flavonoidal Agents in Alzheimer’s Disease PART II: RECENT DEVELOPMENTS AND ADVANCEMENTS IN THE DELIVERY OF NUTRACEUTICALS ACROSS BLOOD-BRAIN-BARRIER 9. Drug Delivery Strategies for Drug Targeting for Alzheimer’s Disease 10. Nanocargos for Efficient Delivery of Nutraceuticals Across Blood-Brain Barrier 11. Recent Advancement in Strategies for Delivery of Neuronutraceuticals to the Brain
| Erscheint lt. Verlag | 15.10.2024 |
|---|---|
| Zusatzinfo | 33 Illustrations, black and white |
| Verlagsort | Oakville |
| Sprache | englisch |
| Maße | 156 x 234 mm |
| Themenwelt | Medizin / Pharmazie |
| Naturwissenschaften ► Biologie ► Humanbiologie | |
| Naturwissenschaften ► Biologie ► Zoologie | |
| Technik ► Lebensmitteltechnologie | |
| ISBN-10 | 1-77491-944-3 / 1774919443 |
| ISBN-13 | 978-1-77491-944-6 / 9781774919446 |
| Zustand | Neuware |
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