The Subcommissural Organ

The subcommissural organ is a secretory ependymo-glial structure of the brain. It secretes glycoproteins into the cerebrospinal fluid. This text includes coverage of experimental models and aims to stimulate further investigations into molecular and systemic aspects of the problem.

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The subcommissural organ is a secretory ependymo-glial structure of the brain. It secretes glycoproteins into the cerebrospinal fluid. The chemical nature of this material is only partly known, and the functional role of the entire circumventricular complex has remained enigmatic. New experimental models include transplantation, immunological blockade, and experimental and clinical hydrocephalus. This book in the field contains provocative ideas and will most likely stimulate further investigations into molecular and systemic aspects of the problem.