Protein and Peptide Therapeutics

David B. Teplow, Ph.D., is a Professor of Neurology, Emeritus, at UCLA and an internationally recognized leader in efforts to understand and treat Alzheimer's disease. Dr. Teplow's group has used a multi-disciplinary approach to determine how neurotoxic peptides, such as the amyloid ß-protein (Alzheimer's disease) and a-synuclein (Parkinson’s disease), form neurotoxic structures that kill neurons and to develop the means to block these processes. Dr. Teplow received undergraduate training at UC Berkeley; a Ph.D. from the University of Washington; and was a postdoctoral scholar at Caltech. Before coming to UCLA, Dr. Teplow was a faculty member in the Department of Neurology, Harvard Medical School. Dr. Teplow has published >250 peer-reviewed articles, books and book chapters, and commentaries, in addition to serving on numerous national and international scientific advisory boards. Dr. Teplow was a founding editor of the Journal of Molecular Neuroscience and Current Chemical Biology, He is Co-Editor-in-Chief of the Elsevier serial Progress in Molecular Biology and Translational Science and is Associate Editor-in-Chief of the American Journal of Neurodegenerative Disease.

Preface
David Teplow
1. Targeting Myc with protein drugs
Jumi Shin
2. Peptide-Based Inhibitors of Epigenetic Proteins
Jasmin Mecinovic and Jordi Hintzen
3. TBA
Charles Chen
4. Peptide Pharmacology: Pioneering Interventions for Alcohol Use Disorder
Abilash Valsala Gopalakrishnan, Ramkumar Katturajan and Sabina Evan Prince
5. Peptides on Patrol: Carrier Systems for Targeted Delivery
Vivek P. Chavda
6. Daptomycin: Mechanism of Action, Mechanisms of Resistance, Synthesis and Structure-activity Relationships
Scott Taylor and Ryan Moreira
7. Delivery of Protein Therapeutics and Vaccines Using their Multivalent Complexes with Synthetic Polyelectrolytes
Alexander K. Andrianov
8. DELIVERY OF THERAPEUTIC PROTEINS TO OCULAR TISSUES: BARRIERS, APPROACHES, REGULATORY CONSIDERATIONS AND FUTURE PERSPECTIVES
Divyesh Harshadkumar Shastri
9. TBA
Gopal Singh Bisht
10. Peptidomimetics Design and Characterization: Bridging Experimental and Computer-Based Approaches
Daniele Di Marino, ALICE ROMAGNOLI and Domenico Raimondo
11. Vaccines Reimagined: The Peptide Revolution in Disease Prevention
Vivek P. Chavda
12. Surface Modified Proteins and Peptides: A new arm of targeted drug delivery
Vivek P. Chavda
13. Oral Delivery of Protein and Peptide
Vivek P. Chavda and Pankti Balar