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Lipid Rafts and Caveolae

From Membrane Biophysics to Cell Biology

Christopher J. Fielding (Herausgeber)

Buch | Hardcover

XVI, 278 Seiten

2006 | 1. Auflage
Wiley-VCH (Verlag)
978-3-527-31261-0 (ISBN)

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This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the subject in detail.Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent scientist in the field, chapters include:Historical backgroundDistinct structures and functionsStructural basisSignalingViral entry and virion buddingCholesterol transportCaveolinsLipid shellsCell polarity and intracellular traffickingCancer cellsOf prime importance to molecular and cell biologists, biochemists, membrane scientists, cancer researchers, and virologists.

Christopher Fielding is Neider Professor of Cardiovascular Physiology at the University of California at San Francisco (UCSF). He graduated from University College in London (UK) where he also received his PhD. After appointments at Oxford University and at the University of Chicago, he joined the faculty at UCSF in 1971, being appointed full professor in 1985. Professor Fielding's main research interest is in the trafficking of cholesterol, its regulation and its role in signal transduction.

Lipid Rafts, Caveolae, and Membrane Traffic
The Forces that Shape Caveolae
The Biophysical Characterization of Lipid Rafts
The Role of Caveolae and Noncaveolar Rafts in Endocytosis
Role of Cholesterol in Signal Transduction from Caveolae
Phosphorylation of Caveolin and Signaling from Caveolae
Role of Lipid Microdomains in the Formation of Supramolecular Protein Complexes and Transmembrane Signaling
Caveolin and its Role in Intracellular Chaperone Complexes
The Roles of Caveolae and Caveolin in Cell Shape, Locomotion, and Stress Fiber Formation
Lipid Rafts in Trafficking and Processing of Prion Protein and Amyloid Precursor Protein
Caveolae and the Endothelial Nitric Oxide Synthase
The Role of Caveolin-1 in Tumor Cell Survival and Cancer Progression

"...Eine sehr gute Übersicht zum Thema bei angemessenem Preis."
BDI, 06/2007

Erscheint lt. Verlag	9.1.2006
Sprache	englisch
Maße	170 x 240 mm
Gewicht	690 g
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
Themenwelt	Naturwissenschaften ► Chemie ► Organische Chemie
Schlagworte	Biochemie • Biochemie u. Chemische Biologie • Biochemistry (Chemical Biology) • Biomolecules (DNA, RNA, Peptides, etc.) • Biomoleküle (DNA, RNA, Peptide) • Biophysik • Biowissenschaften • Cell Biology • Chemie • Chemistry • Life Sciences • Lipide • Medical Cell Biology • Medizinische Zellbiologie • Membran (Biologie) • Molekularbiologie • Zellbiologie
ISBN-10	3-527-31261-7 / 3527312617
ISBN-13	978-3-527-31261-0 / 9783527312610
Zustand	Neuware