Adrenoceptors

Introduction: a short history of adrenoceptor research.- Structures of Adrenoceptors.- Genetic Variants of Adrenoceptors.- Adrenoceptors: Receptors, Ligands and Their Clinical Uses, Molecular Pharmacology and Assays.- Signalling of adrenoceptors: canonical pathways and new paradigms.- Presynaptic Adrenoceptors.- Roles of b-adrenoceptor subtypes and therapeutics in human cardiovascular disease:- heart failure, tachyarrhythmias and other cardiovascular disorders.- Adrenoceptors and Hypertension.- Adrenoceptors in the Lower Urinary Tract.- Asthma and COPD: A Focus on b-Agonists - Past, Present and Future.- Adrenoceptors in the Eye- Physiological and Pathophysiological Relevance.- Adrenoceptors: A Focus on Psychiatric Disorders and Their Treatments.- Locus Coeruleus and Noradrenergic Pharmacology in Neurodegenerative Disease.- Clinical use of adrenergic receptor ligands in acute care settings.- Adrenoceptor expression and function in the endocrine pancreas.- b-adrenoceptors in cancer: old players and new perspectives.