Chemical Genomics

Small Molecule Probes to Study Cellular Function
Buch | Hardcover
XIV, 179 Seiten
2006
Springer Berlin (Verlag)
978-3-540-27865-8 (ISBN)
160,49 inkl. MwSt
Chemical genomics is a highly interdisciplinary and very exciting field of research both in academics and in the life sciences industry. The Ernst Schering Research Foundation Workshop 58 was organized to bring together scientific leaders in the field to discuss the implications of chemical genomics for drug discovery. Various aspects of the interface between chemistry and biology are covered in this volume, such as chemogenomics efforts in the pharmaceutical industry, diversity-oriented synthesis, chemogenomic approaches to the study of cell function, screening technologies, and natural products as tools in chemical biology.

Hilmar Weinmann studied Chemistry at the universities of Tübingen and Hannover (Germany). He joined Schering in 1995, where he is currently a department head of Medicinal Chemistry. His main fields of expertise are in oncology, dermatology and gender healthcare.

Chemogenomics in Drug Discovery.- Chemogenomics Strategies for GPCR Hit Finding.- Chemogenomics Approaches to GPCR Lead Finding.- Diversity-Oriented Synthesis: A Challenge for Synthetic Chemists.- Probing Protein Function with Small Molecules.- Tamoxifen-Based Probes for the Study of Estrogen Receptor-Mediated Transcription.- Protein Structure Similarity Clustering (PSSC) and Natural Product Structure as Guiding Principles for Chemical Genomics.- Novel Strategies in Drug Discovery: Current Challenges in Biomolecular Screening.

Erscheint lt. Verlag 19.4.2006
Reihe/Serie Ernst Schering Foundation Symposium Proceedings
Zusatzinfo XIV, 179 p.
Verlagsort Berlin
Sprache englisch
Maße 148 x 210 mm
Gewicht 385 g
Themenwelt Naturwissenschaften Chemie Organische Chemie
Schlagworte Biology • Chemical biology • Chemical genomics • Chemogenomics • Diversity-oriented synthesis • Gen-Analyse / Genom-Analyse • natural product • Screening • transcription
ISBN-10 3-540-27865-6 / 3540278656
ISBN-13 978-3-540-27865-8 / 9783540278658
Zustand Neuware
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