Antibiotic Resistance Protocols

Using the Zebrafish Larval Model of Infection to Investigate Antibiotic Efficacy and Combination Treatments Against Staphylococcus aureus.- Three-Dimensional Rotary Culture to Model Mycobacterial Biofilms in Low-Shear Detergent-Free Liquid Suspension.- Rapid Gene Silencing Followed by Antimicrobial Susceptibility Testing for Target Validation in Antibiotic Discovery.- Modified HT-SPOTi: An Antimicrobial Susceptibility Testing to Evaluate Formulated Therapeutic Combinations Against Bacterial Growth and Viability.- Investigating Combination Therapy as a Means to Enhance Activity and Repurpose Antimicrobials.- Investigating Photoactive Antimicrobials as Alternatives (or Adjuncts) to Traditional Therapy.- Using Hollow Fiber to Model Treatment of Antimicrobial Resistant Organisms.- A Microtitre Plate Assay at Acidic pH to Identify Potentiators that Enhance Pyrazinamide Activity Against Mycobacterium tuberculosis.- Within-Host Mathematical Models of Antibiotic Resistance.- Use of Individual-Based Mathematical Modelling to Understand More About Antibiotic Resistance Within-Host.- Monitoring Live Mycobacteria in Real-Time Using a Microfluidic Acoustic-Raman Platform.- Phylogenetic Survival Analysis.- Rapid Drug Susceptibility Testing to Preserve Antibiotics.- Quantifying Viable M. tuberculosis Safely Obviating the Need for High Containment Facilities.- Improved Diagnosis and Treatment Monitoring Tuberculosis Using Stool and the Tuberculosis Bacterial Load Assay (TB-MBLA).- Application of Pathogen Genomics to Outbreak Investigation.- Use of Whole Genome Sequencing for Mycobacterium tuberculosis Complex Antimicrobial Susceptibility Testing.- Use of Whole Genome Sequencing for Mycobacterium tuberculosis Complex Antimicrobial Susceptibility Testing: From Sequence Data to Resistance Profiles.- Analysis of Whole Genome Sequencing Data for Detection of Antimicrobial Resistance Determinants.