An Introduction to Molecular Biotechnology

Professor Michael Wink studied Biology in Bonn and Braunschweig, Germany. After post-doctoral work in Cologne and Munich he took up a professorship at the University of Mainz, Germany. Since 1989 Michael Wink has been Professor of Pharmaceutical Biology at the University of Heideberg and was appointed Director of the Institute of Pharmacy and Molecular Biotechnology in 2002. His scientific interests focus on bioactive natural products, pharmacology & toxicology of natural products, and molecular evolution. Professor Wink is author of numerous scientific papers and pharmaceutical biology books.

I INTRODUCTION
Fundamentals of Molecular and Cell Biology
II STANDARD METHODS IN MOLECULAR BIOTECHNOLOGY
Chromatography and Electrophoresis
Enzymes for Modification of Nucleic Acids and Proteins
DNA/RNA Isolation
Nucleic Acids Hybridisation
PCR
DNA Sequencing
Cloning Techniques
Gene Expression
Protein Isolation and Separation Techniques
Immunological Methods
Labeling of Proteins and in situ-Techniques
Electrophysiology
Cell Cycle Measurements
Microscopy
Lasersystems, Fluorescens
Intracellular Lokalisation
Single Molecule Spectroscopy

III Key Topics
Genomics
Funktional Genomics
Proteomics
Protein-Protein und Protein-Nucleic Acids Interactions
Bioinformatics
Drug Development
Drug Targetting
Structural Biology
Recombinant Antibodies
Phage Display
Diagnostics
Macromolecular Drugs
Knock-out Mice
Gene Therapy
PNAs, RNA/DNA-Derivatives
Katalytic RNAs
Katalytic Processes; Enzyme Technology
"Classical" Biotechnology

IV BIOTECHNOLOGY IN INDUSTRY
Opportunities, Risks and Public Acceptance
Patenting Issues
Biotech-Industry: Market and Opportunities
Marketing
Company Foundation