Anandamide in Health and Disease

Dr. Bernard Le Foll is a Clinician Scientist specializing in Addiction. He is Chair of Addiction Psychiatry within the Department of Psychiatry of University of Toronto. He is Head of the Translational Addiction Research Laboratory in the Campbell Family Mental Health Research Institute. He is also the Lead, Clinical Research Innovation Service within the Addiction Division at CAMH. He is Head of the Alcohol Research and Treatment Clinic at CAMH. He is Professor at University of Toronto in the departments of Family and Community Medicine, Pharmacology and Toxicology, Psychiatry ,Institute of Medical Sciences and Dalla Lana School of Public Health.

PART I Introduction to anandamide 1 Regulation of the levels of anandamide and its bioactive congeners by biosynthesis and degradation Vincenzo Di Marzo and Cristoforo Silvestri 2 Imaging the endocannabinoid enzyme fatty acid amide hydrolase in the living human brain Claire Shyu, Shamantha Lora, Laura M. Best, Sheldon Bereznick and Isabelle Boileau 3 Anandamide: From modulation of neuronal excitation to antimicrobial activities--What is in common? Ronit Vogt Sionov and Doron SteinbergPART II Anandamide in diseases 4 Anandamide and mood disorders Jacklynn M. Fitzgerald and Cecilia J. Hillard 5 Anandamide and anxiety Sara Liane Kroll and Leah M. Mayo 6 Anandamide and disease. Role in stress, fear, and PTSD Luke J. Ney and Allison Matthews 7 Anandamide in disease: Role in psychosis M. Belen Blasco, Carlos A. Pretell Annan and Romina Mizrahi 8 Anandamide in personality disorders Nathan J. Kolla and Michelle De Pol 9 A brief review of anandamide in cannabis use and cannabis use disorder Raesham Mahmood, Claudia Poluga, Isabelle Boileau and Laura M. Best 10 Anandamide signaling dysfunction in the development of alcohol use disorders Balapal S. Basavarajappa 11 Role of Anandamide in Nicotine Addiction Bernard Le Foll 12 The role of anandamide in the sleep--wake cycle Monica Mendez Diaz, Yalitza Azucena Alvarado Ramirez, Aline Ostos Valverde, Oscar E. Prospero Garcia and Andrea M. Herrera Solis 13 Anandamide in disease: The good and bad in epilepsy Renaud Gom, Pasindu Wickramarachchi, Roberto Colangeli and G. Campbell Teskey 14 Role of anandamide in Alzheimer’s disease Dina Medina-Vera and Simone Tambaro 15 The role of anandamide in digestive and defensive functions of the gut Keith A. Sharkey and Derek K.L. Tsang 16 The role of anandamide and the endocannabinoids in the treatment and regulation of nausea and vomiting Erin M. Rock and Linda A. Parker