Handbook of Proteolytic Enzymes

Currently Dr. Neil Rawlings is a Senior Scientist in the Proteins Department at the EMBL-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK. Dr. Rawlings has been an active researcher at the Wellcome Trust Sanger Institute for over twenty years. He is extremely well known in the proteolytic enzyme community for his work curating the MEROPS database, an information resource covering peptidases and the proteins that inhibit them, which is used by expert researchers and students worldwide. Dr. Rawlings has published widely in such peer reviewed journals as Genome Research, BMC Bioinformatics, PloS ONE, Nucleic Acids Research, the Journal of Biological Chemistry, and Science.

Volume 1: Metallopeptidases
Volume 2: Serine and threonine peptidases
Volume 3: Cysteine peptidases
Volume 4: Aspartic and glutamic peptidases, asparagine peptide lysases, and peptidases of unknown catalytic mechanisms
Volume 5: Naturally-occurring and synthetic inhibitors of proteolytic enzymes.

CYSTEINE PEPTIDASES (Volume 3) New chapters Pseudotzain Falcipain-2 Falcipain-3 Rhodesain OTULIN peptidase Ubiquitinyl hydrolase-BAP1 Butelase 1 CED-3 peptidase Caspase-11 Metacaspase-9 Middle East respiratory syndrome coronavirus papain-like peptidase Ubiquitin-specific peptidase 9X Ubiquitin-specific peptidase 11 Ubiquitin-specific peptidase 12 Ubiquitin-specific peptidase 18 Ubiquitin-specific peptidase 19 Ubiquitin-specific peptidase 20 Ubiquitin-specific peptidase 21 Ubiquitin-specific peptidase 26 Ubiquitin-specific peptidase 28 Ubiquitin-specific peptidase 30 Ubiquitin-specific endopeptidase 39 MERS coronavirus picornain 3C-like peptidase D-alanyl-glycyl peptidase Autophagin-1 DJ-1 putative peptidase Major revisions Papain Stem bromelain Actinidin Cathepsin B Cathepsin K Cathepsin L Cathepsin S Cathepsin X Falcipain-2 Falcipain-3 Dipeptidyl-peptidase I Peptidase 1 (mite) Cruzipain Calpain-1 Calpain-2 Calpain-3 Streptopain Ubiquitinyl hydrolase-L1 Severe acute respiratory syndrome coronavirus papain-like peptidase Ubiquitin-specific peptidase 4 Ubiquitin-specific peptidase 7 Ubiquitin-specific peptidase 15 Legumain (plant beta form) Legumain, animal-type Caspase-1 Caspase-3 Caspase-7 Caspase-8 Caspase-9 Gingipain K Separase (Homo sapiens-type) Sindbis virus-type nsP2 peptidase Enterovirus picornain 2A Tobacco etch virus NIa peptidase SARS coronavirus picornain 3C-like peptidase Calicivirin