Livestock Genome Editing Tools
Academic Press Inc (Verlag)
978-0-12-819099-9 (ISBN)
Written by international experts who have been working on livestock genetic editing field for more than 30 years, this book provides extensively theoretical and practical experience for readers to master the latest developments. This book explores the importance of research and application, as well as operation procedures, of livestock genetic editing tools. The writing of operation details makes this book an accessible read.
This book is an important resource for researchers interested in genome-edited animals and scientists and technicians in breeding institutions and is also of interest to students major in animal reproduction and biological engineering.
Dr. Kui Li is a Professor at Chinese Academy of Agricultural Sciences. He graduated from Wuhan University of China and appointed as a full Professor at Huazhong (Central China) Agricultural University and Chinese Academy of Agricultural Sciences in China since 1996, respectively. He used to be a visiting scholar at the University of Sydney, Australia and a full-time visiting Professor at the Cornell University, USA. Prof. Li’s research interests include pig genome and breeding, pig genetic engineering, experimental mini-pigs and medical models. He has been working on these fields for more than 3 decades. Since 1996, Prof. Li systematically compared the multi-omics of different developmental stages of Chinese and Western pig breeds and found lots of multi-level molecular markers. He also identified several hundreds of molecular markers related to porcine economic traits which are used to develop pig breeds. He established steady platforms for porcine somatic cell nuclear transfer, pronuclear injection, and genome editing techniques. He also established the techniques to develop genetic modified pigs with multi-gene compound traits, controllable expression and friendly gene locus site directed integration. Excitingly, Prof. Li’s research group generated more than 20 new breeding materials for agriculture including MSTN-edited pigs, anti-porcine reproductive and respiratory syndrome pigs. His research group also generated genome edited pigs for biomedicine including cardiovascular disease and diabetes models, which showed great application perspective. Prof Li is a founder of Agsino Gensources Co., Ltd., an animal biotechnology breeding company. Dr. Bingyuan Wang is an Associate Professor at the Institute of Animal Sciences, Chinese Academy of Agricultural Sciences. In 2014, she graduated from Max Planck Institute for Molecular Biomedicine in Germany. From 2015 to 2023, she worked in the Porcine Gene Engineering and Plasma Innovation group, which is led by Prof. Kui Li. Her research interests include the molecular mechanisms underlying porcine spermatogonial cells proliferation and apoptosis, the influence of exogenous factors in the porcine reproduction using porcine oocytes and spermatogonial cells, induction of gametes from porcine spermatogonial cells, and the generation of genome-edited pigs using porcine spermatogonial cells.
The development of genome editing technology in animals
New tools for genome editing
Associated technologies for genome editing
Application status of genome-editing tools in pig
Application state of genome-editing tools in cattle
Application status of genome-editing tools in sheep and goat
Evaluation and detection of genome-edited livestock
Breeding by molecular writing: the future development of livestock breeding
Erscheinungsdatum | 27.04.2024 |
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Zusatzinfo | 137 illustrations (67 in full color); Illustrations, unspecified |
Verlagsort | San Diego |
Sprache | englisch |
Maße | 152 x 229 mm |
Gewicht | 450 g |
Themenwelt | Naturwissenschaften ► Biologie ► Zoologie |
Weitere Fachgebiete ► Land- / Forstwirtschaft / Fischerei | |
ISBN-10 | 0-12-819099-X / 012819099X |
ISBN-13 | 978-0-12-819099-9 / 9780128190999 |
Zustand | Neuware |
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