The Practice of Medicinal Chemistry -

The Practice of Medicinal Chemistry

Camille Georges Wermuth (Herausgeber)

Buch | Hardcover
896 Seiten
1996
Academic Press Inc (Verlag)
978-0-12-744640-0 (ISBN)
168,35 inkl. MwSt
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This text covers the practical aspects of how medicinal chemists search for, and design, new drugs entities. The focus is on the chemistry, rather than pharmacological concepts or description of the various therapeutic classes of drugs.
This book collects in one single volume, the practical aspects of Medicinal Chemistry, seen from a chemical point of view, including the wealth of information which chemists accumulate over a career, but generally is never organized and presented in a coherent form in print. Emphasis is given to how medicinal chemists conduct their search for, and design of, new drug entities. In contrast to other books on the market, it focuses on the chemistry, rather than pharmacological concepts or description of the various therapeutic classes of drugs. It should become a standard reference on the tools available to medicinal chemists when designing new drugs.

General aspects of medicinal chemsitry; drug targets and lead compound discovery strategies; primary exploration of structure-activity relationships; substituents and functions - qualitative and quantitative aspects of structure-activity relationships; spatial organization, receptor mapping and molecular modelling; chemical modifications influencing the pharmacokinetic properties; pharmaceutical and chemical formulation problems; development of new drugs - legal and economic aspects.

Erscheint lt. Verlag 22.2.1996
Zusatzinfo index
Verlagsort San Diego
Sprache englisch
Maße 17 x 25 mm
Gewicht 1990 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Naturwissenschaften Chemie Organische Chemie
Technik
ISBN-10 0-12-744640-0 / 0127446400
ISBN-13 978-0-12-744640-0 / 9780127446400
Zustand Neuware
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