Hematopoiesis -

Hematopoiesis

Biochemical, Cellular, Molecular, and Genomic Perspectives

Ravi Kumar Gutti (Herausgeber)

Buch | Hardcover
288 Seiten
2024
Apple Academic Press Inc. (Verlag)
978-1-77491-472-4 (ISBN)
186,95 inkl. MwSt
Discusses the concerns of hematopoietic challenges, offering a comprehensive overview of the regulation of blood cell development, epigenetic mechanisms, and regulatory non-coding RNAs. It presents concepts related to regulation of hematopoietic stem cell development, as well as survival, proliferation, and differentiation.
This new volume discusses the widespread concerns of hematopoietic challenges in different and emerging ways. With chapters written by faculty and researchers from prestigious institutions working directly in hematopoiesis and advanced areas of biology, the volume offers a comprehensive overview of the regulation of blood cell development, epigenetic mechanisms, and regulatory non-coding RNAs. It presents concepts related to regulation of hematopoietic stem cell development, as well as survival, proliferation, and differentiation. It also discusses the microenvironmental niche where stem cells exist and develop into distinct blood cell types. A model system used to study non-coding RNA functions along with transformation of normal cells into cancer cell is elaborated on as well.

Key features of the book:



Details how to utilize the available investigative tools and techniques to isolate and study single blood cells in different model systems
Discusses the epigenetics of hematopoiesis
Considers the clinical outcomes of defective hematopoiesis
Describes hematopoiesis and cancer stem cells
Looks at hematopoiesis in relation to specific diseases, such as minimal residual disease (MRD) and leukemia

This book provides valuable information related to developments in hematopoiesis that will be helpful for understanding the basics of hematopoiesis and the clinical treatment of blood diseases. Hematopoiesis: Biochemical, Cellular, Molecular, and Genomic Perspectives will be valuable to clinicians, medical school students, and researchers working in hematology.

Ravi Kumar Gutti, PhD, is Professor in the Department of Biochemistry of the School of Life Sciences at the University of Hyderabad, India. He has extensive research and teaching experience from Harvard Medical School (USA), National Institutes of Health (USA), Moffitt Cancer and Research Centre (USA), and RWTH Aachen (Germany). His research primarily focuses on understanding the molecular mechanisms in low platelet diseases and is well funded by several grants from the Government of India and other organizations. He has received awards and recognition from several prominent national and international organizations, including a Chancellor's Award from the University of Hyderabad for making significant contributions to teaching and research. Dr. Gutti has authored several publications in reputed international journals and has presented his research at international scientific meetings.

1. Unrevealing the Mechanism of Zebrafish Hematopoiesis: A Novel Approach 2. Investigative Tools to Study Blood Cells: Focus on Single Cell Isolation and Analysis 3. Evaluation of Chitosan and Its Derivatives in Immunomodulating Blood Sentinel Cells 4. Proteoglycans and Glycosaminoglycans Regulating Functions of the Hematopoietic Stem Cell Niche 5. Epigenetics of Hematopoiesis: Role of HATs and HDACs 6. Systems Biology Approaches Toward Understanding Human Long Non-Coding RNA Hematopoietic Cells 7. Clinical Outcomes of Defective Hematopoiesis 8. Circulating Messengers of Blood and Their Clinical Applications 9. Hematopoiesis and Cancer Stem Cells: The Seed and the Soil Crosstalk 10. lncRNAs in Types of Leukaemia 11. Minimal Residual Disease (MRD) as a Prognostic Factor in Acute Myeloid Leukaemia

Erscheinungsdatum
Reihe/Serie Modern Trends in Molecular Biology
Zusatzinfo 23 Tables, black and white; 19 Illustrations, color; 4 Illustrations, black and white
Verlagsort Oakville
Sprache englisch
Maße 156 x 234 mm
Gewicht 748 g
Themenwelt Schulbuch / Wörterbuch
Medizin / Pharmazie Allgemeines / Lexika
Medizinische Fachgebiete Innere Medizin Hämatologie
Naturwissenschaften Biologie Biochemie
ISBN-10 1-77491-472-7 / 1774914727
ISBN-13 978-1-77491-472-4 / 9781774914724
Zustand Neuware
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