Stem Cell-Based Neural Model Systems for Brain Disorders

Generation of Cerebral Cortical Neurons from Human Pluripotent Stem Cells in 3D Culture.- Generation of Homogeneous Populations of Cortical Interneurons from Human Pluripotent Stem Cells.- Generation and Co-Culture of Cortical Glutamatergic and GABAergic Induced Neuronal Cells.- Transcription Factor-Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells.- Directed Differentiation of Human iPSCs into Microglia-Like Cells Using Defined Transcription Factors.- The Generation and Functional Characterization of Human Microglia-Like Cells Derived from iPS and Embryonic Stem Cells.- Modeling Cellular Crosstalk of Neuroinflammation Axis by Tri-Cultures of iPSC-Derived Human Microglia, Astrocytes, and Neurons.- Generation of Oligodendrocytes from Human Pluripotent and Embryonic Stem Cells.- Characterizing the Neuron-Glial Interactions by the Co-Cultures of Human iPSC-Derived Oligodendroglia and Neurons.- Defined Differentiation of Human Pluripotent Stem Cells to Brain Microvascular Endothelial-Like Cells for Modeling the Blood-Brain Barrier.- Modeling the Blood-Brain Barrier Using Human Induced Pluripotent Stem Cells.- A Three-Dimensional Primary Cortical Culture System Compatible with Transgenic Disease Models, Virally-Mediated Fluorescence, and Live Microscopy.- Method to Generate Dorsal Forebrain Brain Organoids from Human Pluripotent Stem Cells.- A 3D Bioengineered Neural Tissue Model Generated from Human iPSC-Derived Neural Precursor Cells.- FACS-Based Sequencing Approach to Evaluate Cell Type to Genotype Associations Using Cerebral Organoids.- Dynamic Measurement of Endosome-Lysosome Fusion in Neurons Using High-Content Imaging.- Live-Imaging Detection of Multivesicular Body-Plasma Membrane Fusion and Exosome Release in Cultured Primary Neurons.- Assays of Monitoring and Measuring Autophagic Flux for iPSC-Derived Human Neurons and Other Brain Cell Types.- Measuring Neuronal Network Activity Using Human Induced Neuronal Cells.- A Simple Ca2+-Imaging Approach of Network-Activity Analyses for Human Neurons.- Whole Cell Patch Clamp Electrophysiology in Human Neuronal Cells.- Assaying Chemical Long-Term Potentiation in Human iPSC-Derived Neuronal Networks.