Motor System Disorders, Part I

David S. Younger MD DrPH, MPH MS, Affiliate Professor of Neuroscience at City University of New York Medical School and Attending Physician at White Plains Hospital, NY, has vast experience in both clinical and academic neurology and public health. He mentors students at his alma mater Columbia University College of Physicians and Surgeons. He has been Board certified in Neurology, Internal Medicine, Electrodiagnostic Medicine (AANEM) and Neurophysiology (ABCN). As Associate Editor of the Seminars in Neurology he prepared the 1st edition of his widely-acclaimed textbook, Motor Disorders, now in its 4th edition. He is best recognized as a highly trained electrophysiologist and neuromuscular specialist. For the past decade his work has focused on autoimmunity of the nervous system and the use of immunotherapy and most recently, in COVID-19 neurological illnesses. He is the author of Human Lyme Neuroborreliosis, Science of Medical Cannabis, The Vasculitides, and The Autoimmune Brain; and he has been Guest Editor of the multiple volumes of the Neurological Clinics. He has also authored more than 300 peer-reviewed articles, book chapters, correspondence and scientific abstracts on a wide variety of topics.

Section 1. Normal Physiology and Function 1. Skeletal muscle structure, physiology, and function 2. Upper and lower motor neuron neurophysiology and motor control 3. Vestibular motor control 4. Autonomic failure: Clinicopathologic, physiologic, and genetic aspects 5. Gait control by the frontal lobe 6. Parietal control of hand movement 7. Immunology and microbiome: Implications for motor systems 8. COVID-19 (novel SARS-CoV-2) neurological illness

Section 2. Clinical and Laboratory Diagnosis 9. Neurogenetic motor disorders 10. Neuromuscular electrodiagnosis 11. Quantitative electrodiagnosis of the motor unit 12. Neuromuscular pathology 13. Electrophysiological assessment of peripheral and central autonomic disorders 14. On the path to evidence-based therapy in neuromuscular disorders 15. Advances in the neuroimaging of motor disorders 16. Sleep-related motor disorders

Section 3. Neuromuscular Disorders 17. Neonatal and infantile hypotonia 18. Autoimmune inflammatory myopathies 19. Childhood muscular dystrophies 20. Distal myopathy 21. Muscle channelopathies 22. Congenital myopathies 23. Mitochondrial encephalomyopathy 24. Autoimmune polyneuropathies 25. Hereditary neuropathy 26. Acute/chronic inflammatory polyradiculoneuropathy 27. Myasthenia gravis and congenital myasthenic syndromes 28. Adult and childhood vasculitis 29. Critical illness-associated weakness and related motor disorders