PCR Applications in Pathology

The aim of this work is to present, in a simplified form, the applications of PCR in the area of infectious and inherited diseases. It makes various techniques readily available to the non-molecular biologists who require them.

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The polymerase chain reaction has revolutionised molecular biology by allowing the amplification and characterisation of minute amounts of nucleic acids. As well as being of use to basic scientists, this technique is of immense importance to pathologists who routinely need to detect and characterise small amounts of infectious micro-organisms, or to identify mutations within small amounts of human DNA. This essential handbook clearly and concisely outlines the applications of PCR in the area of infectious and inherited diseases so that methods can be readily used by non-molecular biologists who need them. This book is intended for practising clinical biochemists, clinical chemists, pathologists, and others working in diagnostic laboratories.