The Networking of Chaperones by Co-Chaperones (eBook)

eBook Download: PDF
2022 | 3rd ed. 2023
XV, 429 Seiten
Springer International Publishing (Verlag)
978-3-031-14740-1 (ISBN)

Lese- und Medienproben

The Networking of Chaperones by Co-Chaperones -
Systemvoraussetzungen
181,89 inkl. MwSt
  • Download sofort lieferbar
  • Zahlungsarten anzeigen

Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is the dynamic integration of the processes of protein folding, degradation and translocation to ensure that cellular function is finely tuned in space and time. 

This third edition of the book The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by co-chaperones, a diverse cohort of non-client proteins. Since the second edition was released, not only has knowledge deepened on how co-chaperones act as nodes to network and functionalise chaperones, but an understanding of their broader biological function has started to emerge. The third edition provides new and updated chapters highlighting recent developments and emerging themes on co-chaperones, such as their extracellular functions, their role in human disease and their status as putative drug targets. 

The book is a useful resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology. 



Adrienne L. Edkins:

Adrienne Edkins is Associate Professor of Biochemistry at Rhodes University where she holds a South African Research Chair (SARChI) in Molecular and Cellular Biology of the Eukaryotic Stress Response from the Department of Science and Innovation/National Research Foundation. Her research interests focus on understanding molecular mechanisms by which molecular chaperones, particularly Hsp70-Hsp90 chaperone-co-chaperone complexes, regulate cellular processes critical in normal and pathological cell functions. She has been recognised for her research by the award of the Rhodes University Vice Chancellor's Research Award (2015), the national DSI South African Women in Science (SAWiSA) Award for Distinguished Young Scientist in the Natural/Engineering Sciences (2018) and a Newton Fund Advanced Fellowship from the Academy of Medical Sciences (2018-2021). She is a Fellow of the Cell Stress Society International (FCSSI), Fellow of the African Academy of Sciences (FAAS) and Member of the Academy of Science of South Africa (MASSAf).

Gregory L. Blatch:

Professor Gregory Blatch has worked in academia for over 30 years, and his contributions to the academy and the promotion of science more broadly, have been recognized through a number of awards and fellowships (e.g. Senior Fellow of the Cell Stress Society International, FCSSI; Fellow of the Royal Society of South Africa, FRSSAf). He is currently Executive Dean of the Faculty of Health Sciences, Higher Colleges of Technology, UAE (2021-present). Previously, he served as Pro Vice-Chancellor (PVC) Research at The University of Notre Dame Australia (2017-2020) and remains associated as Emeritus Professor. He has developed teaching and research capacity and capability at Departmental, School, Faculty and University-wide levels, with over 10 years experience as a Senior/Executive Leader. His personal research interests fall within the broad field of cellular stress biology, and he is an international leader for his work on the role of stress proteins in disease (e.g. cancer) and infection (e.g. malaria).

Erscheint lt. Verlag 15.12.2022
Reihe/Serie Subcellular Biochemistry
Subcellular Biochemistry
Zusatzinfo XV, 429 p. 53 illus., 46 illus. in color.
Sprache englisch
Themenwelt Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte cellular networks • Chaperone • Conformational folding • Nonclient-binding partners • Post-translational modification • Protein degradation • Protein Folding • protein homeostasis • protein translocation
ISBN-10 3-031-14740-5 / 3031147405
ISBN-13 978-3-031-14740-1 / 9783031147401
Haben Sie eine Frage zum Produkt?
PDFPDF (Wasserzeichen)
Größe: 15,8 MB

DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasser­zeichen und ist damit für Sie persona­lisiert. Bei einer missbräuch­lichen Weiter­gabe des eBooks an Dritte ist eine Rück­ver­folgung an die Quelle möglich.

Dateiformat: PDF (Portable Document Format)
Mit einem festen Seiten­layout eignet sich die PDF besonders für Fach­bücher mit Spalten, Tabellen und Abbild­ungen. Eine PDF kann auf fast allen Geräten ange­zeigt werden, ist aber für kleine Displays (Smart­phone, eReader) nur einge­schränkt geeignet.

Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.

Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.

Mehr entdecken
aus dem Bereich