Separation Techniques Applied to Omics Sciences

Ana Valéria Colnaghi Simionato is an associate professor at Institute of Chemistry of Unicamp. She advises scientific initiation, masters and doctorate students as well as supervises post-doctorate researches in projects related to the investigation of biomolecules or pharmaceuticals compounds in several sample matrices, such as: culture media, blood serum, urine, saliva, medicines and meat using a metabolomics approaches. The instrumental techniques used for this purpose include capillary electrophoresis, liquid chromatography, gas chromatography and mass spectrometry. She is also part of the National Institute of Science and Technology in Bioanalytics.

The new omics era into systems approaches: what is the importance of separation techniques?.- Biological Applications for LC-MS-Based Proteomics.- The role of chromatographic and electromigration techniques in Foodomics.- CE-MS for proteomics and intact protein analysis.- Peptidomics and Capillary Electrophoresis.- Discovery of native protein complexes by liquid chromatography followed by quantitative mass spectrometry.- Capillary electrophoresis based N-Glycosylation analysis in the biomedical and biopharmaceutical fields.- Practical considerations in method development for gas chromatography-based metabolomic profiling.- Capillary electrophoresis-mass spectrometry for metabolomics: possibilities and perspectives.- Liquid Chromatography - Mass Spectrometry for Clinical Metabolomics: An Overview.- Analytical platforms for mass spectrometry-based metabolomics of polar and ionizable metabolites.- Metabolomic data treatment: basic directions of the full process.- Index.