Nutrients in Cancer Prevention and Treatment

Preface.- I. Carcinogenesis.- G Protein Pathways and Regulation of Neoplastic Transformation.- II. Cancer prevention studies: lab studies.- Vitamin E Succinate Inhibits Protein Kinase C:Correlation with Its Unique Inhibitory Effects on Cell Growth and Transformation.- Vitamin E Succinate:Mechanisms of Action as Tumor Cell Growth Inhibitor.- Vitamin D, Gene Expression, and Cancer.- Mechanisms of Cancer Prevention:Effects of Protease Inhibitors on Proteases and Gene Expression.- Antioxidants and Cancer Prevention In Vivo and In Vitro.- Ascorbic Acid and Gastrointestinal Cancer.- Biochemistry and Pharmacology of Retinoids in Relation to Chemoprevention of Cancer.- Involvement of Retinoic Acid Nuclear Receptors in Transcriptional Regulation of Tissue Transglutaminase, the Gene Involved in Apoptosis.- Mechanisms of Dietary Fat-Induced Colon Cancer Promotion.- Calories and Exercise as Modifiers of Cancer Risk.- Polcyclic Aromatic Hydrocarbon—DNA Adducts in Smokers and Their Relationship to Micronutrient Levels and Glutathione-S-Transferase M1 Genotype.- Aspects of Commercial Deep-Fat Frying of Fallafel and Its Relation to Liver Tumor.- III. Cancer prevention studies: human studies.- Antioxidant Vitamins and Cancer:The Physicians’ Health Study and Women’s Health Study.- Beta-Carotene and Antioxidant Nutrients in Oral Cancer Prevention.- Nutritional Prevention Trials for Colorectal Neoplasia.- IV. Cancer treatment studies: lab studies.- Vitamins Induce Cell Differentiation, Growth Inhibition, and Enhance the Effect or Tumor Therapeutic Agents on Some Cancer Cells In Vitro.- Molecular and Biochemical Control of Tumor Growth Following Treatment with Carotenoids or Tocopherols.- Inhibition and Regression of Experimental Oral Cancer by Beta Carotene and Vitamin E:EmergingConcepts.- Novel Approaches to the Prevention of Chemotherapy-Induced Alopecia.- V. Cancer treatment studies: human studies.- Role of Vitamin A and Its Derivatives in the Treatment of Human Cancer.- Use of Vitamins as Adjunct to Conventional Cancer Therapy.- Orthomolecular Treatment of Cancer.