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Cytochrome P450

Structure, Mechanism, and Biochemistry

Paul R. Ortiz de Montellano (Herausgeber)

Buch | Hardcover

690 Seiten

2004 | 3rd ed. 2005
Kluwer Academic/Plenum Publishers (Verlag)
978-0-306-48324-0 (ISBN)

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Cytochrome P450: Structure, Mechanism, and Biochemistry, third edition is a revision of a review that summarizes the current state of research in the field of drug metabolism. Each chapter provides an in-depth review of a given topic, but concentrates on advances of the last 10 years.

Cytochrome P450: Structure, Mechanism, and Biochemistry, third edition is a revision of a review that summarizes the current state of research in the field of drug metabolism. The emphasis is on structure, mechanism, biochemistry, and regulation. Coverage is interdisciplinary, ranging from bioinorganic chemistry of cytochrome P450 to its relevance in human medicine. Each chapter provides an in-depth review of a given topic, but concentrates on advances of the last 10 years.

Models and Mechanisms of Cytochrome P450 Action.- Computational Approaches to Cytochrome P450 Function.- Structures of Cytochrome P450 Enzymes.- Electron Transfer Partners of Cytochrome P450.- Activation of Molecular Oxygen by Cytochrome P450.- Substrate Oxidation by Cytochrome P450 Enzymes.- Inhibition of Cytochrome P450 Enzymes.- Induction of Cytochrome P450 Enzymes.- Hormonal Regulation of Liver Cytochrome P450 Enzymes.- Human Cytochrome P450 Enzymes.- Cytochrome P450 and the Metabolism and Bioactivation of Arachidonic Acid and Eicosanoids.- Cytochrome P450s in Plants.- The Diversity and Importance of Microbial Cytochromes P450.

Zusatzinfo	XX, 690 p.
Verlagsort	New York
Sprache	englisch
Maße	178 x 254 mm
Gewicht	3470 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pharmazie ► PTA / PKA
	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	0-306-48324-6 / 0306483246
ISBN-13	978-0-306-48324-0 / 9780306483240
Zustand	Neuware