Receptor Endocytosis and Signalling in Health and Disease - Part B

Dr. Indra Mani is an Assistant Professor in the Department of Microbiology, Gargi College, University of Delhi (DU), New Delhi, India. He received M.Sc. in Microbiology from Bundelkhand University (BU), Jhansi, UP, India and Ph.D. in Biochemistry from Banaras Hindu University (BHU), Varanasi, UP, India. He completed postdoctoral training in the Department of Physiology, School of Medicine, Tulane University, New Orleans, USA. He has also worked as a Senior Research Officer (SRO) in the Department of Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi, India. He has more than 10 years of research and teaching experience in Microbiology, Molecular Genetics, Cell Signaling, and Bioinformatics. He has published 49 articles in peer reviewed journals and 22 book chapters. He has presented several papers in the different national and international conferences. He has extensive experience in fluorescence/confocal microscopy, receptor internalization, trafficking and signaling, molecular cytogenetics, microbial characterization, and in silico analysis. He serves as a reviewer of peer-reviewed journals and also a member of national and international societies. Dr Vijai Singh is a Professor and Dean (Research & Innovation) at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. He was an Associate Professor in the Department of Biosciences, School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. Prior this this, he was an Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, India and also an Assistant Professor in the Department of Biotechnology at the Invertis University, Bareilly, India. Prior to that, he was a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He received his Ph.D. in Biotechnology from the National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India with a research focus on the development of molecular and immunoassays for diagnosis of Aeromonas hydrophila. His research interests are focused on building novel biosynthetic pathways for production of medically and industrially important biomolecules. Additionally, his laboratory is working on CRISPR-Cas9 tools for genome editing. He has more than 11 years of research and teaching experience in synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has published 100 articles, 70 chapters, 15 books and 3 patents. He serves as an associate editor, editorial board member, and reviewer of several peer-reviewed journals. He is also a member of the Board of Study and Academic Council of Indrashil University and is the Member Secretary of the Institutional Biosafety Committee (IBSC) at the same University.

Preface

Indra Mani and Vijai Singh



Advances in the molecular level understanding of G-protein coupled receptor

Adhiraj Roy

2. Prion receptors, prion internalization, intra- and inter-cellular transport

Luigi Celauro, Marco Zattoni and Giuseppe Legname

3. Internalization of somatostatin receptors in brain and periphery

Zsolt Csaba and Pascal Dournaud

4. Endocytosis of AMPA receptors: Role in neurological conditions

Norbert Bencsik, Carlos Omar Oueslati Morales, Angelika Hausser and Katalin Schlett

5. Endocytosis of dopamine receptor: Signaling in brain

Ichiro Kawahata and Kohji Fukunaga

6. Endocytosis and signaling of 5-HT1A receptor

Ragini, Sakshi, Ashok Saini and Indra Mani

7. Endocytosis of GABA receptor: Signaling in nervous system

Preeti Sharma, B. Sharan Sharma, Hardik Raval and Vijai Singh

8. The endocytosis, trafficking, sorting and signaling of neurotrophic receptors

Katja Burk

9. Endocytosis of glutamate receptor: Signaling in neurological conditions

Prerna Yadav, Mansi Podia, Shashi Prabha Kumari and Indra Mani

10. Nuclear receptor: Structure and function

Pranati Sar

11. CRHR1 endocytosis: Spatiotemporal regulation of receptor signaling

Paula A. dos Santos Claro, Micaela Silbermins, Carolina Inda and Susana Silberstein

12. Amyloid precursor protein in Alzheimer's disease

Rupesh Maurya, Gargi Bhattacharjee, Khushal Khambhati, Nisarg Gohil, Priyanka Singh, Indra Mani, Dinh-Toi Chu, Suresh Ramakrishna, Pau Loke Show and Vijai Singh

13. Integrin receptor trafficking in health and disease

Victor Samuel, Thejaswitha Rajeev, Lariza Ramesh and Ananthalakshmy Sundararaman

14. Synthetic receptors in medicine

Sarita Mishra, Mahima Raval, Vijai Singh and Anand K. Tiwari

15. Receptor biology: Challenges and opportunities

Indra Mani and Vijai Singh