The Oxford Handbook of Neuronal Ion Channels -

The Oxford Handbook of Neuronal Ion Channels

Arin Bhattacharjee (Herausgeber)

Buch | Hardcover
784 Seiten
2023
Oxford University Press Inc (Verlag)
978-0-19-066916-4 (ISBN)
186,95 inkl. MwSt
Neurons are excitable cells. They use ions and electrical signaling to talk to each to other and when they talk to each other, neurons control behavior. The Oxford Handbook of Neuronal Ion Channels is an accessible reference describing the nature and properties of ion channels in neurons. The book explains how ion channels open and close, how they can be selective for specific ions, and how they give rise to action potentials. Included are in-depth chapters discussing specific classes of ion channels: potassium channels, sodium channels, neurotransmitter-gated ion channels and other specialized channels. Throughout the handbook, important insight is provided on the contribution ion channels make to neuronal excitability and to synaptic transmission. The handbook goes further to discuss channelopathies, a group of human diseases such as epilepsy, pain and migraines that can be caused by ion channel dysfunction. For neuroscientists, biophysicists and neuropharmacologists, this handbook is a valuable reference of ion channel biology and function.

Arin Bhattacharjee obtained his Bachelor's degree and Pharmacology Certificate from the University of Alberta in 1992. He completed doctoral training from the University of South Alabama with Dr. Ming Li in 1999 and did postdoctoral training at Yale University with Dr. Leonard Kaczmarek. In 2005 Bhattacharjee was appointed assistant professor at the University at Buffalo and currently he is an associate professor in Pharmacology and Toxicology. Bhattacharjee investigates how sodium-activated potassium channels contribute to neuronal firing in pain-sensing neurons, during inflammation and nerve injury. He has published 40 papers on ion channel biology and function.

Table of Contents

Basic Principles

1. Excitable Membrane Properties of Neurons
Leonard K. Kaczmarek

2. Ion Channel Permeation and Selectivity
Juan J. Nogueira and Ben Corry

3. Gating of Ion Channels
Rene Barro-Soria

Voltage-gated Channels

4. The Voltage-Dependent K+ Channel Family
Hanne B. Rasmussen and James S. Trimmer

5. Potassium Channel Mutations in Epilepsy
Elizabeth E. Palmer

6. The Voltage-Dependent Sodium Channel Family
Mariola Zaleska, Samantha C. Salvage, Andrew J. Thompson, Sivakumar Namadurai, Christopher L.-H. Huang, Trevor Wilkinson, Fiona S. Cusdin, and Antony P. Jackson

7. Specialized Sodium Channels in Pain Transmission
Yucheng Xiao, Zifan Pei, and Theodore R. Cummins

8. Sodium Channelopathies of the Central Nervous System
Paul G. DeCaen, Alfred L. George, Jr., and Christopher H. Thompson

Ligand-gated Channels

9. AMPA and Kainate Receptors
G. Brent Dawe, Patricia M. G. E. Brown, and Derek Bowie

10. N-Methyl-D-Aspartate Receptors
Gary J. Iacobucci and Gabriela K. Popescu

11. Nicotinic Acetylcholine Receptors
Roger L. Papke

12. GABAA Receptor Physiology and Pharmacology
Martin Wallner, A. Kerstin Lindemeyer, and Richard W. Olsen

13. P2X Receptors
Annette Nicke, Thomas Grutter, and Terrance M. Egan

14. Large Conductance Potassium Channels in the Nervous System
Willy Carrasquel-Ursulaez, Yenisleidy Lorenzo, Felipe Echeverria, and Ramon Latorre

15. Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Alessio Masi, Maria Novella Romanelli, Guido Mannaioni, and Elisabetta Cerbai

Other Channels

16. Tandem Pore Domain Potassium Channels
Douglas A. Bayliss

17. TRPC Channels-- Insight from the Drosophila Light Sensitive Channels
Ben Katz, William L. Pak, and Baruch Minke

18. Acid-Sensing Ion Channels
Stefan Gründer

19. TMEM16 Ca2+ Activated Cl- Channels and CLC Chloride Channels and Transporters
Anna Boccaccio and Michael Pusch

Erscheinungsdatum
Reihe/Serie OXFORD HANDBOOKS SERIES
Verlagsort New York
Sprache englisch
Maße 249 x 181 mm
Gewicht 1923 g
Themenwelt Naturwissenschaften Biologie Humanbiologie
Naturwissenschaften Biologie Zoologie
ISBN-10 0-19-066916-0 / 0190669160
ISBN-13 978-0-19-066916-4 / 9780190669164
Zustand Neuware
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