T-Cell Repertoire Characterization

Ligand identification for Orphan MHC-agnostic T-cell receptors by whole genome CRISPR-Cas9 screening.- Discovery of HLA-E-presented epitopes: MHC-E/peptide binding and T cell recognition.- Identification of human antigen-specific T cells using class II MHC tetramer staining and enrichment.- Characterization of KIR+CD8+ regulatory T cells in humans by scRNA- and TCR-seq.- Detection of α-synuclein-specific T cells in Parkinson’s disease.- The intra-tumoural T cell receptor repertoire – steps towards a useful clinical biomarker.- Enriching and Characterizing T-Cell Repertoires from 3’ Barcoded Single-Cell Whole Transcriptome Amplification Products.- Tetramer associated T cell receptor sequencing.- T-cell Repertoire Characterization.- Characterization of mouse CD4 TCR and its targeting antigen.- Rapid identification of MHCII-binding peptides through microsphere-assisted peptide screening (MAPS).- A high throughput strategy for T-Cell Receptor cloning and expression.- Epitope-specific T-cell receptor data and tools in the Immune Epitope Database.- A Bioinformatic Framework for Dissecting the Dynamics of T cells from Single-Cell Transcriptome.- Grouping T-Cell Antigen Receptors by Specificity.- Flexible Distance-Based TCR Analysis in Python with tcrdist3.- Multimodal T cell analysis with CoNGA.