Analytical Electrochemistry 3e

JOSEPH WANG, PHD, is Director of the Center for Bioelectronics and Biosensors at the Biodesign Institute and Professor in the Departments of Chemical & Materials Engineering and Chemistry & Biochemistry at Arizona State University. Dr. Wang has authored six books and more than 680 research papers. He holds fifteen patents and is the recipient of the American Chemical Society's Award in Chemical Instrumentation and the Heyrovsky Medal. He was ranked the "Most Cited Electrochemist in the World" in 1995, and was ranked number five on the ISI list of "Most Cited Researchers in Chemistry" for the period 1995 to 2005.

Preface. Abbreviations and Symbols. 1. Fundamental Concepts. 1.1 Why Electroanalysis? 1.2 Faradaic Processes. 1.2.1 Mass-Transport-Controlled Reactions. 1.2.1.1 Potential-Step Experiment. 1.2.1.2 Potential-Sweep Experiments. 1.2.2 Reactions Controlled by the Rate of Electron Transfer. 1.2.2.1 Activated Complex Theory. 1.3 Electrical Double Layer. 1.4 Electrocapillary Effect. 1.5 Supplementary Reading. Problems. References. 2. Study of Electrode Reactions and Interfacial Properties. 2.1 Cyclic Voltammetry. 2.1.1 Data Interpretation. 2.1.1.1 Reversible Systems. 2.1.1.2 Irreversible and Quasi-reversible Systems. 2.1.2 Study of Reaction Mechanisms. 2.1.3 Study of Adsorption Processes. 2.1.4 Quantitative Applications. 2.2 Spectroelectrochemistry. 2.2.1 Experimental Arrangement. 2.2.2 Principles and Applications. 2.2.3 Electrochemiluminescence. 2.2.4 Optical Probing of Electrode-Solution Interfaces. 2.3 Scanning Probe Microscopy. 2.3.1 Scanning Tunneling Microscopy. 2.3.2 Atomic Force Microscopy. 2.3.3 Scanning Electrochemical Microscopy. 2.4 Electrochemical Quartz Crystal Microbalance. 2.5 Impedance Spectroscopy. Examples. Problems. References. 3. Controlled-Potential Techniques. 3.1 Chronoamperometry. 3.2 Polarography. 3.3 Pulse Voltammetry. 3.3.1 Normal-Pulse Voltammetry. 3.3.2 Differential-Pulse Voltammetry. 3.3.3 Square-Wave Voltammetry. 3.3.4 Staircase Voltammetry. 3.4 AC Voltammetry. 3.5 Stripping Analysis. 3.5.1 Anodic Stripping Voltammetry. 3.5.2 Potentiometric Stripping Analysis. 3.5.3 Adsorptive Stripping Voltammetry and Potentiometry. 3.5.4 Cathodic Stripping Voltammetry. 3.5.5 Abrasive Stripping Voltammetry. 3.5.6 Applications. 3.6 Flow Analysis. 3.6.1 Principles. 3.6.2 Cell Design. 3.6.3 Mass Transport and Current Response. 3.6.4 Detection Modes. Examples. Problems. References. 4. Practical Considerations. 4.1 Electrochemical Cells. 4.2 Solvents and Supporting Electrolytes. 4.3 Oxygen Removal. 4.4 Instrumentation. 4.5 Working Electrodes. 4.5.1 Mercury Electrodes. 4.5.2 Solid Electrodes. 4.5.2.1 Rotating Disk and Rotating Ring Disk Electrodes. 4.5.2.2 Carbon Electrodes. 4.5.2.2.1 Glassy Carbon Electrodes. 4.5.2.2.2 Carbon Paste Electrodes. 4.5.2.2.3 Carbon Fiber Electrodes. 4.5.2.2.4 Diamond Electrodes. 4.5.2.3 Metal Electrodes. 4.5.3 Chemically Modified Electrodes. 4.5.3.1 Self-Assembled Monolayers. 4.5.3.2 Carbon-Nanotube-Modified Electrodes. 4.5.3.3 Sol-gel Encapsulation of Reactive Species. 4.5.3.4 Electrocatalytically Modified Electrodes. 4.5.3.5 Preconcentrating Electrodes. 4.5.3.6 Permselective Coatings. 4.5.3.7 Conducting Polymers. 4.5.4 Microelectrodes. 4.5.4.1 Diffusion at Microelectrodes. 4.5.4.2 Microelectrode Configurations. 4.5.4.3 Composite Electrodes. Examples. Problems. References. 5. Potentiometry. 5.1 Principles of Potentiometric Measurements. 5.2 Ion-Selective Electrodes. 5.2.1 Glass Electrodes. 5.2.1.1 pH Electrodes. 5.2.1.2 Glass Electrodes for Other Cations. 5.2.2 Liquid Membrane Electrodes. 5.2.2.1 Ion Exchanger Electrodes. 5.2.2.2 Neutral Carrier Electrodes. 5.2.3 Solid-State Electrodes. 5.2.4 Coated-Wire Electrodes and Solid-State Electrodes Without an Internal Filling Solution. 5.3 On-line, On-site, and In Vivo Potentiometric Measurements. Examples. Problems. References. 6. Electrochemical Sensors. 6.1 Electrochemical Biosensors. 6.1.1 Enzyme-Based Electrodes. 6.1.1.1 Practical and Theoretical Considerations. 6.1.1.2 Enzyme Electrodes of Analytical Significance. 6.1.1.2.1 Glucose Sensors. 6.1.1.2.2 Ethanol Electrodes. 6.1.1.2.3 Urea Electrodes. 6.1.1.2.4 Toxin (Enzyme Inhibition) Biosensors. 6.1.1.3 Tissue and Bacteria Electrodes. 6.1.2 Affinity Biosensors. 6.1.2.1 Immunosensors. 6.1.2.2 DNA Hybridization Biosensors. 6.1.2.2.1 Background and Principles. 6.1.2.2.2 Electrical Transduction of DNA Hybridization. 6.1.2.2.3 Other Electrochemical DNA Biosensors. 6.1.2.3 Receptor-Based Sensors. 6.1.2.4 Electrochemical Sensors Based on Molecularly Imprinted Polymers. 6.2 Gas Sensors. 6.2.1 Carbon Dioxide Sensors. 6.2.2 Oxygen Electrodes. 6.3 Solid-State Devices. 6.3.1 Ion-Selective Field Effect Transistors. 6.3.2 Microfabrication of Solid-State Sensor Assemblies. 6.3.3 Microfabrication Techniques. 6.3.4 Micromachined Analytical Microsystems. 6.4 Sensor Arrays. Examples. Problems. References. Index.