Notch Signaling Research
Springer-Verlag New York Inc.
978-1-0716-2200-1 (ISBN)
Authoritative and cutting-edge, Notch Signaling Research: Methods and Protocols is an ideal guide for researchers in the field, with techniques that could potentially be applied to study the wider world of other signaling pathways as well.
Using the CRISPR/Cas9 System for Dissection of Functional Sites of the Notch Gene in Drosophila melanogaster.- Screening Mutants by Single Fly Genomic PCR.- Generation of Properly Folded Epidermal Growth Factor-Like (EGF) Repeats and Glycosyltransferases Enables In Vitro O-Glycosylation.- Use of FLP/FRT System to Screen for Notch Signaling Regulators in the Drosophila Wing.- High-Throughput Analysis to Identify Activators of Notch Signaling.- Artificial Notch Signaling Activation Method Using Immobilized Ligand Beads.- Mammalian NOTCH Receptors Activation and Signaling Protocols.- Somatic Clonal Analyses Using FLP/FRT and MARCM System to Understand Notch Signaling Mechanism and Its Regulation.- Analyzing the Interaction of RBPJ with Mitotic Chromatin and Its Impact on Transcription Reactivation upon Mitotic Exit.- Assessing the Roles of Potential Notch Signaling Components in Instructive and Permissive Pathways with Two Drosophila Pericardial Reporters.- Image-Based Single-Molecule Analysis of Notch-Dependent Transcription in Its Natural Context.- An Automatic Stage Identification MATLAB Tool to Reveal Notch Expression Pattern in Drosophila Egg Chambers.- Employing the CRISPR Technology for Studying Notch Signaling in the Male Gonad of Drosophila melanogaster.- Immuno-Localization of Notch Signaling in Mouse Preimplantation Embryos.- Studying the NOTCH Signaling Pathway Activation in Kidney Biopsies.- Exosomes as Carriers for Notch Molecules.- In Vivo and Ex Vivo Experimental Approach for Studying Functional Role of Notch in Pulmonary Vascular Disease.- Metastasis Model to Test the Role of Notch Signaling in Prostate Cancer.- Functional Studies of Genetic Variants Associated with Human Diseases in Notch Signaling-Related Genes Using Drosophila.- Bioinformatics Tools to Understand Notch.
Erscheinungsdatum | 13.06.2022 |
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Reihe/Serie | Methods in Molecular Biology ; 2472 |
Zusatzinfo | 45 Illustrations, color; 11 Illustrations, black and white; XIII, 298 p. 56 illus., 45 illus. in color. With online files/update. |
Verlagsort | New York, NY |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie |
Naturwissenschaften ► Biologie ► Zellbiologie | |
Schlagworte | dysregulation • Notch disease models • Notch regulators • Notch signaling transduction • receptors • signaling pathways |
ISBN-10 | 1-0716-2200-5 / 1071622005 |
ISBN-13 | 978-1-0716-2200-1 / 9781071622001 |
Zustand | Neuware |
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