Flavin-Based Catalysis (eBook)

Radek Cibulka is Full Professor and Head of the Department of Organic Chemistry at the University of Chemistry and Technology (UCT) in Prague, Czech Republic. He has authored over 60 scientific publications and received numerous scientific awards, including "Alfred Bader Prize", which is given by the Czech Chemical Society and the Alfred Bader Foundation to young scientists under 35 years. His research interests lie in chemistry and photochemistry of flavins and their application in organo- and photocatalysis. Marco Fraaije is Full Professor and heading the Molecular Enzymology group at the University of Groningen (RUG) in Groningen, The Netherlands. He has authored over 200 scientific publications and received numerous scientific awards, including the BIOCAT-science award (2018). His research focuses on the discovery, engineering and exploration of redox enzymes, with special emphasis on flavin-containing enzymes. Besides exploring the biocatalytic potential of these biocatalysts, he also aims at elucidating the molecular functioning of (flavo)enzymes.

Structure and properties of flavins
Natural flavins: occurrence, role and non-canonical chemistry
Spectral properties of flavins
Modes of flavin-based catalysis
Organocatalytic monooxygenations
Flavin-based supramolecular and coupled catalytic systems
Flavoprotein monooxygenases and halogenases
Flavoprotein-dependent bioreduction
Flavoprotein oxidases
Benzylic photooxidation by flavins
New applications of flavin photocatalysis
Light-driven flavin-based biocatalysis