Practical Applications of Internal Dosimetry

Originally released as a supplement to Internal Radiation Dosimetry, this book begins with a detailed overview of the anatomy and physiology of organ systems essential to our understanding of radionuclide entry to the body and deposition within internal organs. The authors provide detailed examples and case studies for better understanding of the concepts and theory presented.

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This book was originally released as a supplement to Internal Radiation Dosimetry (1994, Medical Physics Publishing), edited by Otto Raabe. Chapter 1 begins with a detailed overview of the anatomy and physiology of organ systems essential to our understanding of radionuclide entry to the body and deposition within internal organs. Detailed biokinetic models of inhalation, ingestion, and skin entry are then given in Chapter 2. Chapter 3 addresses concepts of exposure and bioassay as needed in internal dose assessment programs. Chapter 4 addresses the design and conduct of these programs, with specific emphasis on current regulatory and legal requirements. Support information to Chapters 3 and 4 are given in Chapter 5 (variance reduction models) and Chapter 6 (fecal monitoring for plutonium and other long-lived actinides). Chapters 7 and 8 cover Bayesian statistics and the use of Markov Chain Monte Carlo, respectively, as applied to internal dosimetry. Medical aspects of internal dosimetry are covered in Chapter 9 (nuclear medicine) and in Chapter 10 (radionuclide therapy). In many of these chapters, the authors provide detailed examples and case studies for better understanding of the concepts and theory presented.