Transcranial Direct Current Stimulation in Neuropsychiatric Disorders

lt;p>André R Brunoni is Associate Professor at the Department of Internal Medicine and Psychiatry, University of São Paulo Medical School, he was also a Visiting Professor at the University of Munich (April-2017 / October-2018) with a research fellowship from CAPES / Alexander Von Humboldt Foundation. He holds a PhD in Neuroscience and Behavior from the Institute of Psychology at USP (2010-2012), and received a doctoral fellowship from Harvard Medical School (Boston, USA). He graduated in Medicine (2004) from University of São Paulo Medical School. He is the Director of the Neuromodulation Interdisciplinary Service of the Institute of Psychiatry, Hospital das Clínicas (FMUSP), Senior Researcher of the Longitudinal Study of Adult Health (ELSA-Brazil). His research interests include depression and mood disorders, and noninvasive neuromodulation in the treatment of mental disorders. He has published more than 300 articles in international peer-reviewed journals, and is currently the editor-in-chief of Archives of Clinical Psychiatry.

Colleen Loo is Professor of Psychiatry at the University of New South Wales, NHMRC Leadership Fellow and Professorial Fellow at the Black Dog Institute, Sydney; Australia. She qualified in medicine and psychiatry in Australia (MB BS, FRANZCP) and completed a research doctorate in 2003 (MD). She was chair of psychiatry at St George Hospital (2006-2021), founded the Neurostimulation service at the Black Dog Institute in 2014, and is Regional Medical Director of ECT and Interventional Psychiatry at the Ramsay Northside Group hospitals in Sydney. She was President of the International Society for ECT and Neurostimulation (2018-2020) and is an editorial board member of the journal Brain Stimulation. Her research interests are in developing novel treatments for depression and other psychiatric disorders, focussing on transcranial magnetic stimulation, transcranial direct current stimulation, electroconvulsive therapy and ketamine, and their effects on brain functioning. She has published over 200 peer-reviewed papers and has received grant funding from the Australian NHMRC, US-based NARSAD and Stanley Foundations, UK NHS/MRC and Singapore NMC.

Michael A Nitsche is a Full Professor at the Department of Psychology and Neurosciences at Leibniz Research Centre for Working Environment and Human Factors, Dortmund. He was a Consultant and Head of the Epilepsy Unit of the Department of Clinical Neurophysiology at University Medicine Goettingen (2006-2015) and Registrar at the same department (1999-2005). He graduated in Psychology from Georg August University Goettingen in 1995 and in Medicine in 1998. He received his MD in 2000. His research fields include non-invasive brain stimulation, physiological foundations of cognition and behavior, and neuropsychopharmacology. He has published more than 200 papers in international, peer-reviewed journals, and is currently a member of the editorial boards of Scientific Reports, and Brain Stimulation.

Part I. Introduction and mechanisms of action.- Chapter 1. Historical aspects of transcranial electric stimulation.- Chapter 2. Basic mechanisms of transcranial alternating current and random noise stimulation.- Chapter 3. Physiology of transcranial direct and alternating current stimulation.- Chapter 4. Animal Models of tES: Methods, Techniques and Safety.- Chapter 5. Animal Studies on the Mechanisms of Low-Intensity Transcranial Electric Stimulation.- Part II. Research Methods.- Chapter 6. TMS-evoked EEG Response in Neuropsychiatric Disorders.- Chapter 7. Multimodal Association of tDCS with Electroencephalography.- Chapter 8. tDCS and Magnetic Resonance Imaging.- Chapter 9. tDCS and Functional Connectivity.- Chapter 10. The value of neuroimaging for treating depression with brain stimulation.- Chapter 11. Target Engagement with Transcranial Current Stimulation.- Chapter 12. Cerebellar and Spinal tDCS.- Chapter 13. Precision targeting of neural networks with tDCS informed by brain mapping.- Chapter 14. Clinical research and methodological aspects for tDCS research.- Part III. TDCS in the life cycle.- Chapter 15. tDCS in Child and Adolescent Psychiatry.- Chapter 16. Transcranial Direct Current Stimulation in the perinatal period.- Chapter 17. Modulating Cognition in Healthy Young Adults with tDCS.- Chapter 18. tDCS in exercise, sport performance and recovery process.- Chapter 19. Transcranial Direct Current Stimulation in Social and Emotion Research.- Chapter 20. Neurodegenerative cognitive disorders.- Part IV. Applications of tDCS in neuropsychiatric disorders.- Chapter 21. Mood disorders: clinical results.- Chapter 22. Effect of transcranial direct current stimulation on hallucinations in patients with Schizophrenia.- Chapter 23. Schizophrenia: Negative Symptoms.- Chapter 24. OCD, Anxiety Disorders, and PTSD.- Chapter 25. Cognitive functions in substance-related and addictive disorders.- Chapter 26. Transcranial Direct Current Stimulation in Substance Use Disorders.- Chapter 27. Attention-deficit/hyperactivity disorder.- Chapter 28. Cognitive effects of transcranial direct current stimulation in clinical trials.- Chapter 29. Epilepsy.- Chapter 30. Pain syndromes.- Chapter 31. Transcranial direct current stimulation for the treatment of tinnitus.- Chapter 32. Transcranial direct current stimulation in disorders of consciousness.- Chapter 33. TDCS in the Context of Rehabilitation.- Part V. The clinical use of tDCS.- Chapter 34. Safety and tolerability.- Chapter 35. Home-based tDCS: applications and approaches, design, feasibility and safety.- Chapter 36. Ethical Aspects of tDCS Use in Neuropsychiatry and the Risk of Misuse.- Chapter 37. tDCS-Pharmacotherapy interactions.- Chapter 38. Combination of tDCS with Psychotherapy and Neurobehavioral Interventions: Systematic Review and Mechanistic Principles for Future Clinical Trials.- Chapter 39. Regulatory aspects.