Introduction to Basics of Pharmacology and Toxicology (eBook)

This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics.

Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. 

This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences. 

Dr. Abialbon Paul completed his M.B.B.S. and M.D. in Pharmacology from Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER). He finished M.B.B.S. with distinction and four gold medals. Currently, he is working as an Assistant Professor of Pharmacology. During his post-graduation, he has been extremely passionate about teaching and research. The editor has been actively involved in the conduction of ethics committee meetings. He has published research articles and reviews in indexed journals and acted as a resource person/ faculty and organizing committee member of various academic programs including conferences, workshops and CMEs. He has been the Clinical Pharmacologist in-charge of the Madurai region of Apollo Hospitals where he had developed Antibiotic Stewardship programs and took charge of the medication management. 

Dr. Nishanthi Anandabaskar has finished her M.B.B.S. and M.D. in Pharmacology from JIPMER, Puducherry.  Currently, she is working as an Assistant Professor in the Dept. of Pharmacology, Sri Manakula Vinayagar Medical College and Hospital (SMVMCH), Puducherry, India. She was awarded the Prof. M.N. Ghosh gold medal (2017) for outstanding performance in Pharmacology. She has also completed the Postgraduate Diploma in Bioethics (PGDBE) from the PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India. She is a member of the Institutional Ethics Committee of SMVMCH, Puducherry and also of the Institutional Ethics Committee for observational studies in JIPMER, Puducherry, India. The editor has co-authored a book chapter on 'Precision medicine in diabetes mellitus' in the book 'Precision Medicine in Cancers and Non-Communicable Diseases' (CRC Press; ISBN: 9781315154749). She has also completed online certificate courses on Professional Diploma in Clinical Research (PDCR) and Advance Certificate Course in Scientific Writing from the Catalyst Clinical Services. Dr. Nishanthi has published research papers in Pharmacology in leading national and international biomedical journals.

Dr. Jayanthi Mathaiyan, M.B.B.S., M.D., D.N.B., is currently working as a faculty (Additional Professor and Head, Dept. of Pharmacology) at JIPMER involved in teaching, research and administrative activities. Dr. Jayanthi  has a teaching experience of over a decade which includes taking lectures, question paper setting and evaluation of medical (M.B.B.S., M.D. Pharmacology), paramedical (B.Sc. Nursing, Medical Lab Technology and related courses) students, conducting orientation programmes to M.B.B.S., M.D. and Ph.D. students. Research activities include conducting & guiding M.B.B.S., M.D. and Ph.D. students for research in areas of interest. She has been involved in research in the fields of rational use of medicines, medication errors, pharmacogenomics and therapeutic drug monitoring for over 10 years. She has guided numerous projects involving research in the areas of medication errors with anticancer drug use, pharmacogenomics of diazepam, metformin and capecitabine. She has co-authored 30 indexed journal publications, both national and international and has also contributed chapters in medical books.

Dr. Gerard Marshall Raj holds an M.B.B.S. and M.D. in Pharmacology. Currently, he is working as an Assistant Professor in the Dept. of Pharmacology, All India Institute of Medical Sciences (AIIMS), Bibinagar, Hyderabad Metropolitan Region, Telangana, India. He has contributed and co-edited the book 'Introduction to Basics of Pharmacology and Toxicology Volume 1: General and Molecular Pharmacology: Principles of Drug action' (Springer-Nature; ISBN: 9789813297784). He has also contributed book chapters in other books, namely, 'Intellectual Property Rights in Drug Development and Biotechnology' in the book 'Intellectual Property Issues in Biotechnology' (CABI; ISBN: 9781780646534), 'Intellectual Property Issues Surrounding Antimicrobial Agents' in the book 'Intellectual Property Issues in Microbiology' (Springer-Nature; ISBN: 9789811374654), and 'The Pharmacogenetics of Metformin' in the book 'The Pharmacological Guide to Metformin' (Nova Science Publishers; ISBN: 9781536166347). He was awarded the 'Prof. M. N. Ghosh Gold Medal' for outstanding performance during the M.D. Pharmacology course at JIPMER, Puducherry and has published many research articles, reviews, commentaries, case reports, and letters-to-the-editor in peer-reviewed and indexed journals.

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This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics.Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.