Viral Replication Enzymes and their Inhibitors Part A

Craig E. Cameron is at UNC School of Medicine, NC, USA Jamie J. Arnold is at UNC School of Medicine, Chapel Hill, NC, USA

Preface

Craig E. Cameron, Jamie J. Arnold and Laurie S. Kaguni

1. CoV-er all the bases: Structural perspectives of SARS-CoV-2 RNA synthesis

Brandon Malone, Seth A. Darst and Elizabeth A. Campbell

2. Mechanisms of inhibition of viral RNA replication by nucleotide analogs

Kenneth A. Johnson and Tyler Dangerfield

3. HCV RdRp, sofosbuvir and beyond

Joy Y. Feng and Adrian S. Ray

4. Understanding viral replication and transcription using single-molecule techniques

Emmanuelle Pitre and Aartjan J.W. te Velthuis

5. In vitro single-molecule manipulation studies of viral DNA replication

Rebeca Bocanegra, Ismael Plaza-G.A. and Borja Ibarra

6. Allosteric and dynamic control of RNA-dependent RNA polymerase function and fidelity

Dennis S. Winston and David D. Boehr

7. Single-cell analysis for the study of viral inhibitors

Mohamad S. Sotoudegan, Jamie J. Arnold and Craig E. Cameron

8. Structural basis of viral RNA-dependent RNA polymerase nucleotide addition cycle in picornaviruses

Peng Gong

9. Picornaviral 2C proteins: A unique ATPase family critical in virus replication

Pu Chen, Zhijian Li and Sheng Cui

10. Flavivirus enzymes and their inhibitors

Ekaterina Knyazhanskaya, Marc C. Morais and Kyung H. Choi

11. Watching the bacterial RNA polymerase transcription reaction by time-dependent soak-trigger-freeze X-Ray crystallography

Yeonoh Shin and Katsuhiko S. Murakami

12. Inhibition of viral RNA-dependent RNA polymerases with clinically relevant nucleotide analogs

Kieran Maheden, Brendan Todd, Calvin J. Gordon, Egor P. Tchesnokov and Matthias Götte