Organic Chemistry

Marc Loudon is the Cwalina Distinguished Professor of Medicinal Chemistry at Purdue University. His teaching awards include the Clark Teaching Prize (at Cornell), Purdue’s School of Pharmacy's Henry Heine Outstanding Teacher Award (1980 and 1985), the Class of 1922 Helping Students Learn Award, the Charles B. Murphy Award, membership in the Teaching Academy of Purdue and listing in Purdue’s permanent “Book of Great Teachers”, and designation as the Carnegie Foundation “Indiana Professor of the Year”. Most recently, Dr. Loudon has been involved in chemistry curriculum re-design for life-science majors and pre-health profession students with the NEXUS program of the Howard Hughes Medical Institute. James Parise is a Teaching Professor in the Department of Chemistry and Biochemistry at the University of Notre Dame, where he lectures organic chemistry. Previously, he taught and coordinated organic chemistry laboratories at Duke University. Dr. Parise’s research interests include development of more effective teaching methods for large lecture courses and improving organic chemistry pedagogy in both the classroom and laboratory. He administers an instructor-training program in organic chemistry and is currently developing auxiliary courses aimed at supplementing student preparation for introductory organic courses.

1. Chemical Bonding and Chemical Structure

2. Alkanes

3. Acids and Bases. The Curved-Arrow Notation

4. Introduction to Alkenes: Structure and Reactivity

5. Addition Reactions of Alkenes

6. Principles of Stereochemistry

7. Cyclic Compounds: Stereochemistry of Reactions

8. Noncovalent Intermolecular Interactions

9. The Chemistry of Alkyl Halides

10. The Chemistry of Alcohols and Thiols

11. The Chemistry of Ethers, Epoxides, Glycols, and Sulfides

12. Introduction to Spectroscopy: Infrared Spectroscopy and Mass Spectrometry

13. Nuclear Magnetic Resonance Spectroscopy

14. The Chemistry of Alkynes

15. Dienes, Resonance, and Aromaticity

16. The Chemistry of Benzene and its Derivatives

17. Allylic and Benzylic Reactivity

18. The Chemistry of Aryl Halides, Vinylic Halides, and Phenols. Transition-Metal Catalysis.

19. The Chemistry of Aldehydes and Ketones. Carbonyl-Addition Reactions.

20. The Chemistry of Carboxylic Acids

21. The Chemistry of Carboxylic Acid Derivatives

22. The Chemistry of Enolate Ions, Enols, and a,b- Unsaturated Carbonyl Compounds

23. The Chemistry of Amines

24. Carbohydrates

25. The Chemistry of Thioesters, Phosphate Esters, and Phosphate Anhydrides

26. The Chemistry of the Aromatic Heterocycles; DNA

27. Amino Acids, Peptides, and Proteins

28. Pericyclic Reactions