The Peripheral T-Cell Lymphomas (eBook)

About the Editors Owen A. O'Connor, American Cancer Society Research Professor, Professor of Medicine, Department of Medicine, Division of Hematology and Oncology, Program for T-cell Lymphoma Research, Department of Microbiology, Immunology, and Cancer Research, University of Virginia Cancer Center, Charlottesville, VA, USA. Won Seog Kim, MD, PhD is Professor of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. Pier Luigi Zinzani, MD, PhD is Professor of Hematology, Director of Lymphoma and CLL Unit, and Chief of Phase I clinical trials, Institute of Hematology, University of Bologna, Italy.

List of contributors to be generated by the copy editor

Part 1: Biological Basis of the Peripheral T-Cell Lymphomas

1 Fundamentals T-Cell Lymphocyte Biology

Claudio Tripodo, Stefano Pilleri

2 Mechanisms of T-cell Lymphomagenesis

François Lemonnier, Philippe Gaulard, Laurence de Leval

3 Epigenetics of T-cell Lymphoma

H. Miles Prince, Jasmine Zain, Anas Younes, Sean Whittaker, Owen O'Connor, Sean Harrop

4 Animal Models of T-cell Lymphoma

Keiichiro Hattori, Raksha Shrestha, Tatsuhiro Sakamoto, Manabu Kusakabe, Mamiko Sakata-Yanagimoto

Part 2: Epidemiology and Classification of the PTCL

5 The Geographic Distribution of the PTCL: Global Epidemiology

Amulya Yellala, Avyakta Kallam, James Armitage

6 Classification of the Peripheral T-Cell Lymphomas

Neval Ozkaya, Elaine Jaffee

7 Molecular Classification of the PTCLs

Tyler A. Herek, Javed Iqbal

Part 3: Discrete Clinical Subtypes of PTCL (Unique Epidemiology, Therapy and Management)

8 Peripheral T-Cell Lymphoma - Not Otherwise Specified

Nora Bennani, Stephen Ansell

9 Angioimmunoblastic T-cell Lymphoma (AITL)

Jehan Dupuis, Franck Morschhauser

10 The Spectrum of Anaplastic Large Cell Lymphoma

Jianping Kong, Andrew Feldman

11 HTLV-1-Positive Adult T-Cell Leukemia-Lymphoma (ATL)

Wataru Munakata, Kensei Tobinai

12 Natural Killer/T Cell Lymphomas

S.J. Kim, R. Suzuki, A. Jaccard, S.T. Lim, Won Seog Kim

13 T-Prolymphocytic Leukemia (T-PLL)

Dima El-Sharkawi, Claire Deardon

14 Large Granular Lymphocytes Leukemia (LGL)

Karolina H. Dziewulska, Katharine B. Moosic, HeeJin Cheon, Kristine C. Olson, David J. Feith, Thomas P. Loughran, Jr.

15 Gamma Delta T-cell Lymphomas

Francine Foss, Aadil Ahmed, Mina Xu

16 Enteropathy Associated T-Cell Lymphoma and Monomorphic Epitheliotropic Intestinal T-cell lymphoma

Craig R. Soderquist, Jennifer Shingleton, Sandeep Dave, Govind Bhagat

17 Hepatosplenic T-Cell Lymphomas

Robert N. Stuver, Mwanasha Merrill, Salvia Jain

18 Cutaneous T-Cell Lymphoma

Alejandro Ariel Gru, Bethanie Rooke, Kevin Molloy, Julia Scarsbrick

19 Other Rare Subtypes of PTCL

Pier Paolo Picaluga

Part 4: Treatment of the PTCL

20 Standard Front-line Therapies

Raphael Koch, Lorenz Truemper

21 Approved Agents in the Relapsed or Refractory Setting, Excluding Brentuximab vedotin

Helen Ma, Owen A. O'Connor

22 The Role for Autologous Stem Cell Transplantation (ASCT) in Peripheral T Cell Lymphomas (PTCL)

Juan Alejandro Ospina, H. Martinez-Cordero, J. Enciso, H. Idrobo

23 Allogeneic Stem Cell Transplantion

Anna Dodero, Paolo Corradini

24 Emerging Immunotherapy Approaches in Peripheral T-Cell Lymphomas

Barbara Pro, Andrei Shustov

25 Emerging New Small Molecules in Peripheral T-Cell Lymphomas

Alessandro Broccoli, Pier Luigi Zinzani

Part 5: Future Directions

26 The Value and Relevance of T-cell Lymphoma Registries

Tetiana Skrypets, Martina Manni, Monica Civallero, Iryna Kriachok, Massimo Federico

27 Innovative Chemotherapy-Free Approaches for the Treatment of PTCL

Enrica Marchi, Ahmed Sawas, Helen Ma, Luigi Scotto, Francesca Montanari

28 Global Collaborations

Dejan Radjeski, Eliza Hawke, Owen A. O'Connor, Pier Luigi Zinzani, WonSeog Kim, Enrica Marchi