Advances in Nanochemoprevention (eBook)

This book discusses the recent progress and advances in nanochemoprevention. Chemoprevention utilizes natural dietary compounds and has regained interest due to larger safety window and proven efficacy of such molecules in cancer treatments. Nanotechnology has revolutionized drug delivery through passive as well as active targeting. This book provides a comprehensive overview of phytochemical bioactives that are used in chemoprevention. It gives a comprehensive overview of the variety of natural molecules and types of nanoparticles as well as mechanistic aspects of their superior efficacy over plain drug molecules. The book concludes with summarizing the progress of pre-clinical results of developed formulations for cancer treatment using nano-chemoprevention.

Dr. Rishi Paliwal is presently working as Assistant Professor in Department of Pharmacy, Indira Gandhi National Tribal University, Amarkantak, MP. He has completed his bachelor, master and doctorate degree in pharmaceutical sciences from the Department of Pharmaceutical Sciences, Dr. H. S. Gour Vishwavidyalaya (A Central University), Sagar, MP, India which is one of prestigious and oldest pharmacy institutes in India. Dr. Paliwal completed his Post Doctorate from Rangel College of Pharmacy, Texas A&M University, USA. Dr. Paliwal has contributed substantially to research on novel drug delivery, drug targeting and nano-biotechnology involving colloidal drug carriers customized for targeted drug delivery. Dr. Paliwal is a recipient of young scientist award given by Madhya Pradesh Council of Science and Technology, Bhopal for his research efforts in the area of nanomedicine and nanobiotechnology. He has 11 years of teaching and research experience in the field of pharmaceutical sciences. Dr. Paliwal is also a recipient of Rudlof Cimdins Award (European Society of Biomaterials) and Career Award for Young Teachers (AICTE, New Delhi). He has been awarded as outstanding Assistant Professor in Pharmaceutics award by association of pharmacy teachers of India-MP Branch. He has delivered talk in several national and international conferences. His research areas of interest includes applications of nanotechnological principles in drug delivery, drug targeting, lymphatic delivery of therapeutic molecules through oral route, non-invasive delivery of macromolecules such as protein and peptide including vaccine delivery, intracellular drug delivery and controlled delivery of phytopharmaceuticals. He has published 40 research/review papers in high impact internationally reputed journals. He has contributed to 15 book chapters in the leading international books of material sciences, nanoscience and pharmaceutical sciences. He has participated and presented his research work in several international conferences in India and aboard i.e. Switzerland, Singapore, France, and USA. Dr. Paliwal serves as reviewer of many international journals including International Journal of Pharmaceutics, AAPS Scitech, Colloid and Surface B, International Journal of Nanomedicine, Expert Opinion on Drug Delivery, Drug Delivery etc. He served as Guest Editor of special issue of Journals 'Current Drug Therapy' and 'Mini-Reviews in Medicinal Chemistry'. Presently, he is serving as editorial advisory board member of Current Drug Therapy (Bentham Science Publishers) since 2016. Dr. Paliwal is project investigator of three (03) funded projects worth (Rs. 75.0 Lakhs) of DBT, New Delhi and UGC, New Delhi. He has supervised 07 master students and is supervising 02 PhD scholars for their thesis at present.

Dr. Shivani Rai Paliwal holds the position of senior Assistant Professor in the Department of Pharmaceutical Sciences in Guru Ghasidas Viswavidyalaya (A Central University), Bilaspur, Chhatisgarh, India since 2011. She completed her doctorate from Department of Pharmaceutical Sciences, Dr. H. S. Gour Vishwavidyalaya (A Central University), Sagar, MP, India.  Dr. Paliwal has experience of 11 years in teaching and research. She is recipient of many awards including Young Women Scientist Award by council of science and technology of the MP, Rudolf Cimdins Award by European Society of Biomaterials (ESB), Switzerland, Fast Track Young Scientist Award by Department of Science and Technology (DST) and Travel award by ISBN, Singapore. She has published more than 38 research and review articles in international journal of high repute and authored about 15 book chapters in edited books. She delivered her talk at various national and international platforms and for that visited Switzerland, France, Singapore and USA. Her research area include cancer drug targeting using ligand anchored nanocarriers and non-invasive bioroutes for advanced drug delivery. She has been guest editor of special issue of Journals 'Current Drug Therapy' and 'Mini-Reviews in Medicinal Chemistry'. Dr. Paliwal is supervising students for their Master and PhD since last eight years. Dr. Paliwal has completed a research project as project investigator funded by SERB, DST, New Delhi and another project is ongoing funded by ICMR, New Delhi as PI in the area of nanochemoprevention. 

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This book discusses the recent progress and advances in nanochemoprevention. Chemoprevention utilizes natural dietary compounds and has regained interest due to larger safety window and proven efficacy of such molecules in cancer treatments. Nanotechnology has revolutionized drug delivery through passive as well as active targeting. This book provides a comprehensive overview of phytochemical bioactives that are used in chemoprevention. It gives a comprehensive overview of the variety of natural molecules and types of nanoparticles as well as mechanistic aspects of their superior efficacy over plain drug molecules. The book concludes with summarizing the progress of pre-clinical results of developed formulations for cancer treatment using nano-chemoprevention.