A-Beta Metabolism and Alzheimer's Disease

Takaomi Comings Saido (Autor)

Buch | Hardcover

179 Seiten

2003
CRC Press (Verlag)
978-1-58706-230-8 (ISBN)

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This book provides information regarding three major aspects of Aβ metabolism: generation from its precursor, degradation within the brain, and transport out of the brain. It is useful for graduate students, post-doctoral fellows, and scientists both in this and other disciplines.

Saido, Takaomi Comings

1. Overview—Aß Metabolism: From Alzheimer Research to Brain Aging C o n tro 2. ß-Secretase: Progress and Open Questions 3. APP a-Secretase, a Novel Target for Alzheimer Drug Therapy 4. ?-Secretase and Presenilin 5. Functional Roles of APP Secretases 6. Proteolytic Degradation of Aß by Neprilysin and Other Peptidase 7. Aß Degradation by Endothelin-Converting Enzymes 8. Aß Metabolism in Cholesterol Enriched Membrane Microdomains 9. Amyloid ß-Protein in Low-Density Membrane Domains 10. Transport-Clearance Hypothesis for Alzheimer’s Disease and Potential Therapeutic Im plication 11. Potential Role of Endogenous and Exogenous Aß Binding Molecules in Aß Clearance and M etabolism 12. Modulating Amyloid-ß Levels by Immunotherapy: A Potential Therapeutic Strategy for the Prevention and Treatm ent of Alzheimer’s Disease

Verlagsort	London
Sprache	englisch
Maße	152 x 229 mm
Gewicht	544 g
Themenwelt	Medizin / Pharmazie ► Allgemeines / Lexika
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
	Medizin / Pharmazie ► Pflege ► Altenpflege
	Naturwissenschaften ► Biologie
ISBN-10	1-58706-230-5 / 1587062305
ISBN-13	978-1-58706-230-8 / 9781587062308
Zustand	Neuware