Principles of Neural Science

Eric R. Kandel, MD
University Professor, Department of Neuroscience
Professor and Director, Kavli Institute for Brain Science
Senior Investigator, Howard Hughes Medical Institute
Columbia University

Part I: Overall Perspective
Chapter 1: The Brain and Behavior
Chapter 2: Genes and Behavior
Chapter 3: Nerve Cells, Neural Circuitry, and Behavior
Chapter 4: The Neuroanatomical Bases by Which Neural Circuits Mediate Behavior
Chapter 5: The Computational Bases of Neural Circuits That Mediate Behavior
Chapter 6: Imaging and Behavior

Part II: Cell and Molecular Biology of Cells of the Nervous System
Chapter 7: The Cells of the Nervous System
Chapter 8: Ion Channels
Chapter 9: Membrane Potential and the Passive Electrical Properties of the Neuron
Chapter 10: Propagated Signaling: The Action Potential

Part III: Synaptic Transmission
Chapter 11: Overview of Synaptic Transmission
Chapter 12: Directly Gated Transmission: The Nerve-Muscle Synapse
Chapter 13: Synaptic Integration in the Central Nervous System
Chapter 14: Modulation of Synaptic Transmission and Neuronal Excitability: Second Messengers
Chapter 15: Transmitter Release
Chapter 16: Neurotransmitters

Part IV: Perception
Chapter 17: Sensory Coding
Chapter 18: Receptors of the Somatosensory System
Chapter 19: Touch
Chapter 20: Pain
Chapter 21: The Constructive Nature of Visual Processing
Chapter 22: Low-Level Visual Processing: The Retina
Chapter 23: Intermediate-Level Visual Processing and Visual Primitives
Chapter 24: High-Level Visual Processing: From Vision to Cognition
Chapter 25: Visual Processing for Attention and Action
Chapter 26: Auditory Processing by the Cochlea
Chapter 27: The Vestibular System
Chapter 28: Auditory Processing by the Central Nervous System
Chapter 29: Smell and Taste: The Chemical Senses

Part V: Movement
Chapter 30: Principles of Sensorimotor Control
Chapter 31: The Motor Unit and Muscle Action
Chapter 32: Sensory-Motor Integration in the Spinal Cord
Chapter 33: Locomotion
Chapter 34: Voluntary Movement: Motor Cortices
Chapter 35: The Control of Gaze
Chapter 36: Posture
Chapter 37: The Cerebellum
Chapter 38: The Basal Ganglia
Chapter 39: Brain-Machine Interfaces

Part VI: The Biology of Emotion, Motivation, and Homeostasis
Chapter 40: The Brain Stem
Chapter 41: The Hypothalamus: Autonomic, Hormonal, and Behavioral Control of Survival
Chapter 42: Emotion
Chapter 43: Motivation, Reward, and Addictive States
Chapter 44: Sleep and Wakefulness

Part VII: Development and the Emergence of Behavior
Chapter 45: Patterning the Nervous System
Chapter 46: Differentiation and Survival of Nerve Cells
Chapter 47: The Growth and Guidance of Axons
Chapter 48: Formation and Elimination of Synapses
Chapter 49: Experience and the Refinement of Synaptic Connections
Chapter 50: Repairing the Damaged Brain
Chapter 51: Sexual Differentiation of the Nervous System

Part VIII: Learning, Memory, Language and Cognition
Chapter 52: Learning and Memory
Chapter 53: Cellular Mechanisms of Implicit Memory Storage and the Biological Basis of Individuality
Chapter 54: The Hippocampus and the Neural Basis of Explicit Memory Storage
Chapter 55: Language
Chapter 56: Decision-Making and Consciousness

Part IX: Diseases of the Nervous System
Chapter 57: Diseases of the Peripheral Nerve and Motor Unit
Chapter 58: Seizures and Epilepsy
Chapter 59: Disorders of Conscious and Unconscious Mental Processes
Chapter 60: Disorders of Thought and Volition in Schizophrenia
Chapter 61: Disorders of Mood and Anxiety
Chapter 62: Disorders Affecting Social Cognition: Autism Spectrum Disorder
Chapter 63: Genetic Mechanisms in Neurodegenerative Diseases of the Nervous System
Chapter 64: The Aging Brain