Benzodiazepine-Based Drug Discovery

Farzad Zamani obtained his PhD from University of Wollongong (Australia) in 2019 under the supervision of Professor Stephen Pyne and Dr. Christopher Hyland. His research included development of transition metal-catalyzed cyclization reactions and heterocycle synthesis. Currently, he is a JSPS postdoctoral fellow in the group of Professor Takayoshi Suzuki at Osaka University working on investigation of small molecule inhibitors of RNA/epigenetic protein complexes in drug discovery.Farzad Zamani obtained his PhD from University of Wollongong (Australia) in 2019 under the supervision of Professor Stephen Pyne and Dr. Christopher Hyland. His research included development of transition metal-catalyzed cyclization reactions and heterocycle synthesis. Currently, he is a JSPS postdoctoral fellow in the group of Professor Takayoshi Suzuki at Osaka University working on investigation of small molecule inhibitors of RNA/epigenetic protein complexes in drug discovery. Esmail Doustkhah received his PhD in 2017 in the field of catalysis and organic chemistry. In his PhD, he received several awards and scholarships. Currently, he is a JSPS fellow at NIMS in the group of Professors Y. Yamauchi and Y. Ide. His research areas include silicate nanosheet, mesoporous materials, and titania nanostructures for (photo)(bio)catalysis.

1. An Introduction to Benzodiazepines 2. Chemical Structure of 1,4-Benzodiazepines 3. Synthesis of 1,4-Benzodiazepines 4. Biological Behavior of 1,4-Benzodiazepines 5. Pharmaceutical Applications of 1,4-Benzodiazepines 6. Chemical Structure of 1,5-Benzodiazepines and 1,5-Benzothiazepines 7. Synthesis of 1,5-Benzodiazepines and 1,5-Benzothiazepines 8. Biological Behavior of 1,5-Benzodiazepines and 1,5-Benzothiazepines 9. Pharmaceutical Applications of 1,5-Benzodiazepines 10. Pharmaceutical Applications of 1,5-Benzothiazepines